Main features Detection, by allelic discrimination, of the DPYD gene polymorphisms (IVS10C>G, HapB3, c.1236G>A), DPYD*13 (c.1679T>G), DPYD*2A (IVS14+1G>A, c.1905+1G>A), DPYD c.2846>T, DPYD c.2194G>A, associated with the toxicity due to the treatment with fluoropyrimidines, using 4 oligo mixes. Each mix allows the co-amplification of the mutant sequence (FAM) as well as the wild-type sequence (HEX).
Controls DPYD WT positive control: Positive control DNA containing a mixture of synthetic wild-type DNA sequences for DPYD polymorphisms analyzed. DPYD MT positive control: Positive control DNA containing a mixture of synthetic mutant DNA sequences for DPYD polymorphisms analyzed.
Starting material The kit allows the analysis of genomic DNA extracted from whole blood.
Execution time 2 hours.
هنوز بررسیای ثبت نشده است.