Easy® KRAS

Attributes

  • product-brand: Diatech Pharmacogenetics

🇬🇧 Easy® KRAS Kit | Sensitive Detection of KRAS Mutations in Cancer Samples

Manufacturer: Diatech Pharmacogenetics – Italy
Exclusive Distributor in Iran: Fardad Azma Rad Co.
Certification: ✅ CE-IVD Certified


🧬 Product Overview

The Easy® KRAS Kit by Diatech Pharmacogenetics (Italy) is a high-sensitivity real-time PCR assay designed for the detection of clinically relevant KRAS mutations commonly found in colorectal, lung, and pancreatic cancers.
Using 12 dedicated oligo mixes, this kit provides full mutation coverage across exons 2, 3, and 4, enabling reliable detection of mutant alleles at very low frequencies (as low as 0.5%) even in wild-type–dominant DNA samples.


🔬 Key Features

  • Targeted Mutations:

    • Exon 2: Codons 12, 13

    • Exon 3: Codons 59, 61

    • Exon 4: Codons 117, 146

  • Technology: Co-amplification of mutant (FAM) and internal control (HEX) sequences

  • DNA Quality Control: Dedicated oligo mix to assess sample integrity and DNA quantity

  • Controls Included:

    • Positive control DNA for all targeted mutations

    • Horizon KRAS G12V 1% reference standard

  • Sensitivity (LOD): Detects mutant alleles down to 0.5%

  • Sample Types: FFPE, fresh, or frozen tumor tissue

  • Run Time: ~2 hours

  • Certification: CE-IVD


💡 Applications

  • KRAS mutation screening for targeted therapy selection

  • Molecular diagnostics in oncology and pathology laboratories

  • Suitable for precision medicine workflows


🌐 Fardad Azma Rad Co.

Fardad Azma Rad Co. is the exclusive representative of Diatech Pharmacogenetics (Italy) in Iran and the authorized supplier of molecular oncology diagnostic kits, including Easy® KRAS.
The company provides high-quality diagnostic products, scientific consultation, and technical support to pathology and molecular laboratories across Iran.

Sensitivity

  • The kit can detect very low percentages of mutant alleles, even in the presence of high amounts of wild-type DNA.

  • Limit of Detection (LOD):
    As low as 0.5% using FAM and HEX-labeled probes.

Raw Materials

  • Suitable for analysis of DNA extracted from fresh, frozen, and formalin-fixed, paraffin-embedded (FFPE) tissue samples.

Run Time

  • Approximately 2 hours for the complete analysis.

Why Choose KRAS Mutation Detection Kit?

  • Highly Sensitive: Detects even the smallest amounts of mutant alleles, essential for accurate cancer diagnosis.

  • Comprehensive Coverage: Identifies all relevant mutations in the KRAS gene, crucial for personalized treatment decisions.

  • Easy to Use: Quick, reliable, and easy-to-follow protocol.

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