Titano MSI

Attributes

  • product-brand: Diatech Pharmacogenetics

Titano MSI Kit | Microsatellite Instability (MSI) Detection in Colorectal Cancer

The Titano MSI Kit, manufactured by Diatech Pharmacogenetics (Italy), is a CE-IVD certified molecular diagnostic assay for the detection of Microsatellite Instability (MSI) in colorectal cancer (CRC) and MSI-related tumors.
Using fluorescent multiplex PCR and capillary electrophoresis, the kit enables precise classification of samples as MSI-H (High Instability) or MSS (Stable).

It is ideal for:

  • Lynch Syndrome screening

  • MSI status stratification

  • Immunotherapy treatment planning


🔬 Key Features

  • Fast workflow: Results in under 5 hours

  • Compatible samples: FFPE, fresh/frozen tissues, and peripheral blood

  • Validated instruments: ABI 310, 3130, 3130XL Genetic Analyzers

  • Comprehensive marker coverage:

    • Bethesda panel: BAT25, BAT26, D2S123, D17S250, D5S346

    • Additional markers: BAT40, D18S58, NR21, NR24, TGFßRII

    • Internal controls: TPOX, TH01 for contamination/sample mix-up detection

  • CE-IVD certified and compliant with European quality standards


🌐 Fardad Azma Rad Co.

Fardad Azma Rad Co. is the exclusive representative of Diatech Pharmacogenetics (Italy) in Iran and the official supplier of advanced MSI and pharmacogenetic diagnostic kits.
The company ensures high-quality standards, scientific support, and technical expertise for pathology and molecular laboratories across Iran.

Parameter Description
Product Name Titano MSI Kit
Application Determination of microsatellite instability (MSI) status in colorectal cancer samples
Method Multiplex PCR with fluorescent primers followed by DNA fragment analysis on an automated sequencer
Target Markers BAT25, BAT26, D2S123, D17S250, D5S346, BAT40, D18S58, NR21, NR24, TGFßRII
Control Markers TPOX, TH01 (for detection of contamination or sample mix-ups)
Sample Types DNA extracted from fresh, frozen, paraffin-embedded tissues, and peripheral blood
Procedure Four multiplex amplifications with the same thermal profile, followed by two capillary electrophoresis runs
Total Analysis Time Approximately 5 hours
Kit Size 24 tests (Code: FA001)
Kit Components All necessary reagents for PCR amplification and human genomic DNA as positive control
Validated Instruments ABI 310, ABI 3130, or ABI 3130XL Genetic Analyzer
Certification CE-IVD
Manufacturer Diatech Pharmacogenetics – Italy
Exclusive Representative in Iran Fardad Azma Rad Co.

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