REALQUALITY RQ-HPV HR/LR Multiplex

Product Overview

The REALQUALITY RQ-HPV HR/LR Multiplex kit (CE-IVD) detects HPV DNA from
14 high-risk (HR), 6 possibly high-risk (pHR), and 2 low-risk (LR) genotypes.
It provides specific genotyping of HPV 6/11/16/18 using a robust Multiplex Real-Time PCR system.
This kit is ideal for laboratories needing simultaneous HR/LR differentiation and explicit genotyping of HPV 6, 11, 16, and 18.

Applications

Clinical HPV screening and follow-up that require HR/LR classification plus specific reporting of HPV 6/11/16/18.
Suitable for DNA extracted from a wide range of sample types (refer to IFU for approved specimens).
Recommended for laboratories needing explicit detection of low-risk genotypes (HPV 6/11) for patient counseling.

Key Features

HR (14): 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68
pHR (6): 26, 53, 67, 70, 73, 82
LR (2): 6, 11
Specific genotyping: HPV 6, 11, 16, 18
Multiplex Real-Time PCR for streamlined workflow and reduced cost per reaction
Low DNA input: only 5 µL of extracted DNA required
Carry-over prevention: integrated dUTP/UNG system plus fluorescence normalizer
Internal and positive controls included for full workflow validation
Harmonized thermal profile with other REALQUALITY HPV/STI assays
Compatible with major validated Real-Time PCR instruments
Automated reporting supported by AB Genius Report and GENEQUALITY® platforms

When to Choose This Model

Choose RQ-HPV HR/LR Multiplex if you need HR/LR differentiation together with specific genotyping for HPV 6/11/16/18.
For HR-only screening, consider the RQ-HPV HR Multiplex model.
If broader LR coverage (8 LR genotypes) is required, the RQ-Multi HPV Detection kit is recommended.

Kit Contents

Ready-to-use Multiplex Real-Time PCR reagents
Internal control (IC) and positive control
Instructions for Use (IFU)

🇮🇷 Exclusive Distribution in Iran

Fardad Azma Rad Co. is the exclusive representative of
AB Analitica in Iran. The company provides this HPV kit to clinical and molecular laboratories nationwide, offering:

Guaranteed authenticity for all imported products
Specialized training for end-users
Full technical and scientific support by trained experts

Additional Information:
HPV infection is the most common sexually transmitted infection. Different types of HPV are categorized into low-risk and high-risk groups. High-risk types, especially HPV 16 and 18, are recognized as the main causes of cervical cancer and are also associated with other cancers in genital and non-genital regions. Viral proteins E6 and E7 play crucial roles in carcinogenesis. These proteins, after viral DNA integration into the host DNA, cause uncontrolled cell growth, leading to genetic instability and chromosomal abnormalities.

During viral integration, parts of the HPV DNA may be lost, but the E6 and E7 genes are always preserved. Therefore, using a system targeting these genes reduces the chance of false-negative results.