Easy® DPYD

Easy® DPYD Kit | Detection of DPYD Gene Polymorphisms Related to Fluoropyrimidine Toxicity

Manufacturer: Diatech Pharmacogenetics – Italy
Exclusive Distributor in Iran: Fardad Azma Rad Co.
Certification: ✅ CE-IVD Certified

🧬 Product Overview

The Easy® DPYD Kit enables rapid and accurate detection of key DPYD gene polymorphisms associated with fluoropyrimidine-related toxicity, including 5-fluorouracil (5-FU) and capecitabine.
Developed by Diatech Pharmacogenetics (Italy) and CE-IVD certified, the assay uses allelic discrimination technology to differentiate between mutant and wild-type alleles using four dedicated oligo mixes with high sensitivity and specificity.

🔬 Key Features

• Technology: Co-amplification using FAM (mutant) and HEX (wild-type) probes

• High accuracy in distinguishing DPYD allelic variants

• Positive Control: Synthetic DNA containing wild-type DPYD sequences

• Ideal for pre-treatment pharmacogenetic screening

• Certified CE-IVD for clinical use

🎯 Detected DPYD Variants

• IVS10C>G, HapB3, c.1236G>A

• c.1679T>G (DPYD*13)

• IVS14+1G>A (DPYD*2A), c.2846A>T, c.2194G>A

💡 Applications

• Personalized chemotherapy planning

• Genetic screening prior to 5-FU or capecitabine treatment

• Use in oncology and molecular diagnostic laboratories

🌐 Fardad Azma Rad Co.

Fardad Azma Rad Co. is the exclusive representative of Diatech Pharmacogenetics (Italy) in Iran and the authorized supplier of molecular pharmacogenetic diagnostic kits, including Easy® DPYD.
The company is committed to delivering high-quality diagnostic solutions and expert technical support to oncology and molecular laboratories across Iran.