REALQUALITY RQ-BCR-ABL p190 One-Step

REALQUALITY RQ-BCR-ABL p190 One-Step kit is designed for the detection and quantification of genetic alterations associated with a specific type of leukemia called p190.

Methodology:
This kit uses Real-Time RT-PCR in a single step to perform accurate and rapid detection.

Key Features:

Developed according to standards: Designed based on the “Europe Against Cancer” guidelines and international recommendations.
Contamination prevention: Includes a system to prevent sample contamination.
Sample requirement: Requires only 5 microliters of extracted RNA.
Combined with standard: When used with a specific standard, it allows for detection of additional leukemia-related proteins.
Compatibility: Compatible with other similar kits.

Kit Contents:

Ready-to-use reagents for Real-Time PCR.
Positive control to ensure test validity.

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Additional Information:

Philadelphia chromosome (Ph): The first identified clonal marker in cancer, present in over 95% of Chronic Myeloid Leukemia (CML) cases.
Genetic translocation: This translocation results in production of specific proteins that promote uncontrolled cell growth.
Importance of detection: Identifying these genetic changes is crucial not only for accurate diagnosis and prognosis but also for monitoring residual disease (MRD), guiding treatment decisions.