p63 Antibody (Immunohistochemistry) – Talent Biomedical

Exclusive Distributor in Iran: Fardad Azma Rad Co.

Pathologists use the p63 Antibody to detect myoepithelial and basal cells in several tissues.
These tissues include the prostate, breast, skin, and salivary glands.
As a result, the antibody plays a key role in identifying epithelial differentiation and evaluating tumor behavior.

In addition, p63 belongs to the p53 tumor suppressor gene family.
It supports epithelial development, differentiation, and long-term tissue maintenance.
Therefore, this antibody helps distinguish invasive carcinomas from benign lesions.

Technical Features

• Product Type: p63 primary antibody
• Test Type: Immunohistochemistry (IHC)
• Application: Detection of p63 expression in FFPE tissues
• Positive Localization: Nucleus
• Positive Control: Prostate tissue
• Available Volumes: 0.2 ml, 1 ml, 3 ml, 6 ml, 11 ml
• Storage: 2–8 °C

Clinical Significance

The p63 protein helps distinguish prostatic adenocarcinoma from benign prostatic hyperplasia (BPH).
For example, malignant glands lack p63 expression, while basal cells in BPH show strong positivity.
Moreover, when combined with p40 and CK5/6, p63 supports the diagnosis of squamous cell carcinoma in the head, neck, lung, and breast.

Assay Principle

During the IHC procedure, the primary p63 antibody binds directly to its nuclear antigen.
Next, the secondary HRP-conjugated antibody attaches to the primary antibody and strengthens the signal.
Finally, the DAB chromogen reacts with this complex and produces a clear brown nuclear stain.
Therefore, the staining confirms the presence of the p63 antigen.

Distributor Information

Fardad Azma Rad exclusively distributes Talent Biomedical products in Iran.
Moreover, the company provides complete support and reliable nationwide supply for all IHC diagnostic reagents, including the p63 Antibody.

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