CD7 Antibody (Immunohistochemistry)

Attributes

  • product-brand: Talent biomedical

CD7 Antibody (Immunohistochemistry)

The CD7 Antibody is a key immunohistochemical marker used to identify T-cell neoplasms and related disorders.
CD7 is a 40-kDa transmembrane glycoprotein, a member of the immunoglobulin superfamily, expressed early during T-cell development. It is present on thymocytes, mature peripheral T cells, natural killer (NK) cells, and some lymphoid and myeloid progenitors.

Anti-CD7 antibody is a valuable diagnostic tool for detecting T-cell lymphomas and leukemias, and for differentiating immune-related neoplasms.


🔬 Features and Benefits

  • T-cell specific marker: Detects T-cell lineage and differentiates from other immune cells

  • Clear membrane staining: Brown coloration on the membrane of positive cells

  • Wide diagnostic utility: Essential in identifying T-cell lymphomas and leukemias

  • Compatible with standard IHC protocols: Suitable for both clinical and research laboratories

  • Excellent stability: Reliable performance at 2–8 °C for 18 months


⚙️ Principle of the Assay

During the IHC process, the CD7 antibody binds to the target antigen on the surface of T cells. The HRP-conjugated secondary antibody then binds to the primary antibody, forming the antigen–antibody–HRP complex. The addition of DAB chromogen produces a brown insoluble stain on the membrane of positive cells, confirming antigen expression.


💡 Diagnostic Applications

  • Detection of T-cell lymphomas and leukemias

  • Differentiation of immune system neoplasms

  • Research on T-cell and NK-cell development

  • Evaluation of lymphoproliferative disorders


🌐 Fardad Azma Rad Co.

Fardad Azma Rad Co., the exclusive representative of Talent Biomedical in Iran, supplies advanced immunohistochemistry antibodies, including CD7.
With a focus on precision, reliability, and global standards, the company delivers innovative diagnostic products and molecular pathology solutions to pathology and research laboratories across Iran.

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Specification Details
Product Name CD7 Antibody
Target Antigen CD7 (Cluster of Differentiation 7)
Molecular Weight ~40 kDa
Protein Type Transmembrane glycoprotein, member of the immunoglobulin superfamily
Application Immunohistochemistry (IHC)
Expression Profile Thymocytes, mature peripheral T cells, NK cells, some lymphoid and myeloid progenitors
Positive Localization Cell membrane
Positive Control Tonsil or lymph node tissue
Clinical Significance Key marker for identifying T-cell neoplasms and leukemias; aids in differentiating immune-related malignancies
Principle of the Assay The primary CD7 antibody binds to CD7 antigen on T-cell membranes; HRP-conjugated secondary antibody and DAB chromogen produce brown membrane staining indicating antigen presence
Available Volumes 0.2 ml / 1 ml / 3 ml / 6 ml / 11 ml
Storage Conditions 2 – 8 °C (refrigerated)
Shelf Life 18 months
Manufacturer Talent Biomedical, China
Exclusive Distributor in Iran Fardad Azma Rad Co.

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