STAT6 Antibody (Immunohistochemistry)

Exclusive Distributor of Talent Biomedical in Iran

The STAT6 Antibody is a highly specific marker used for diagnosing Solitary Fibrous Tumor (SFT).
STAT6 is a 94 kDa nuclear transcription factor activated through IL-4 and IL-13 signaling.
As a result, abnormal nuclear expression of STAT6—caused by the NAB2–STAT6 fusion gene—acts as a distinctive diagnostic feature.

In addition, strong nuclear STAT6 staining is considered a sensitive and specific indicator of SFT.
Therefore, it helps pathologists differentiate SFT from other fibroblastic and mesenchymal tumors with greater accuracy.

🔬 Features and Benefits

• Highly specific marker for Solitary Fibrous Tumor
• Clear brown nuclear staining in positive cells
• Useful for differentiating SFT from other fibroblastic tumors
• Compatible with standard IHC protocols
• Reliable performance with an 18-month shelf life at 2–8 °C

⚙️ Principle of the Assay

During the IHC procedure, the primary STAT6 antibody binds directly to its nuclear antigen.
Next, the HRP-conjugated secondary antibody attaches to the primary antibody.
Finally, the DAB chromogen reacts with this complex and produces a brown nuclear stain.
Consequently, this staining confirms STAT6 expression in tumor cells.

💡 Diagnostic Applications

• Diagnosis of Solitary Fibrous Tumor (SFT)
• Differentiation of SFT from other fibroblastic and mesenchymal neoplasms
• Research involving the NAB2–STAT6 fusion gene
• Studies related to IL-4 and IL-13 signaling pathways

🌐 Fardad Azma Rad Co.

Fardad Azma Rad Co. is the exclusive representative of
Talent Biomedical in Iran.
Moreover, the company provides high-quality diagnostic IHC antibodies, including the STAT6 Antibody,
while supporting advanced pathology and molecular diagnostic practices across the country.

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