Desmin Antibody (Immunohistochemistry) – Talent Biomedical

Exclusive Distributor in Iran: Fardad Azma Rad Co.

Pathologists use the Desmin Antibody to detect Desmin protein in muscle-related tissues.
Desmin is a type III intermediate filament that maintains the structural integrity of smooth, skeletal, and cardiac muscle cells.
As a result, this antibody plays a key role in identifying tumors with myogenic differentiation.

In addition, Desmin expression helps distinguish rhabdomyosarcoma, leiomyosarcoma, leiomyoma, and desmoid-type fibromatosis.
Therefore, it serves as a reliable marker for evaluating myofibroblastic lesions and other soft tissue tumors.
Moreover, its clear cytoplasmic staining pattern improves diagnostic accuracy in routine pathology.

Technical Features

• Product Type: Primary antibody specific for Desmin
• Test Type: Immunohistochemistry (IHC)
• Application: Identification of myogenic origin in muscle and soft tissue tumors
• Positive Localization: Cytoplasm
• Positive Control: Skeletal muscle tissue
• Available Volumes: 0.2 ml, 1 ml, 3 ml, 6 ml, 11 ml
• Storage Temperature: 2–8 °C

Clinical Significance

Desmin positivity confirms muscle-cell origin in tumor samples.
Furthermore, this expression supports the diagnosis of rhabdomyosarcoma, leiomyosarcoma, and related soft tissue neoplasms.
Consequently, Desmin contributes to precise tumor classification and improves diagnostic confidence.

Principle of the Assay

During IHC staining, the primary Desmin antibody binds directly to its cytoplasmic antigen.
Next, an HRP-conjugated secondary antibody attaches to the primary antibody.
Finally, the DAB chromogen reacts with this complex and produces a brown cytoplasmic stain.
This stain confirms the presence of Desmin protein in the tissue.

Distributor Information

Fardad Azma Rad exclusively distributes Talent Biomedical products in Iran.
Moreover, the company provides complete technical support and continuous supply of all IHC diagnostic antibodies, including the Desmin Antibody.

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