Calponin Antibody (Immunohistochemistry) – Talent Biomedical

Exclusive Distributor in Iran: Fardad Azma Rad Co.

Pathologists use the Calponin Antibody to detect Calponin protein in tissue samples.
This protein weighs 34 kDa and appears in smooth muscle cells and myoepithelial cells.
As a result, the antibody helps identify smooth muscle differentiation in many neoplasms.

In addition, Calponin interacts with actin, tropomyosin, and calmodulin.
Therefore, it plays an important role in smooth muscle contraction.
Because of its specificity, the antibody helps distinguish benign sclerosing breast lesions from invasive carcinomas.

Technical Features

• Product Type: Calponin primary antibody
• Test Type: Immunohistochemistry (IHC)
• Application: Detection of Calponin in FFPE sections
• Positive Localization: Cytoplasm
• Positive Control: Breast tissue
• Available Volumes: 0.2 ml, 1 ml, 3 ml, 6 ml, 11 ml
• Storage: 2–8 °C

Clinical Significance

Calponin acts as a key marker for smooth muscle and myoepithelial differentiation.
Moreover, evaluating its expression helps pathologists identify benign breast lesions and separate them from invasive carcinomas.
It also assists in assessing myoepithelial presence in multiple tissue types.

Assay Principle

During the IHC procedure, the primary Calponin antibody binds directly to its target antigen.
Next, a secondary HRP-conjugated antibody attaches to the primary antibody.
Finally, the DAB chromogen reacts with the complex and produces a brown cytoplasmic stain, which confirms Calponin expression.

Distributor Information

Fardad Azma Rad exclusively distributes Talent Biomedical products in Iran.
Moreover, the company provides full technical support and ensures a continuous supply of all professional IHC diagnostic reagents, including the Calponin Antibody.

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