{"id":1884,"date":"2025-06-09T14:42:01","date_gmt":"2025-06-09T11:12:01","guid":{"rendered":"https:\/\/fardadazma.com\/en\/?post_type=product&p=1884"},"modified":"2025-11-18T16:15:19","modified_gmt":"2025-11-18T12:45:19","slug":"rabbit-anti-human-egfr-monoclonal-antibody-6-ml","status":"publish","type":"product","link":"https:\/\/fardadazma.com\/en\/product\/rabbit-anti-human-egfr-monoclonal-antibody-6-ml\/","title":{"rendered":"EGFR Antibody Immunohistochemistry"},"content":{"rendered":"

EGFR Antibody (Immunohistochemistry) \u2013 Talent Biomedical<\/h1>\n

Exclusive Representative in Iran: Fardad Azma Rad Co.<\/h2>\n

The EGFR Antibody<\/a> (Immunohistochemistry)<\/strong> is a major biomarker in molecular pathology,
\nused for the detection of Epidermal Growth Factor Receptor (EGFR) in a wide range of epithelial tumors.<\/p>\n

What Is EGFR?<\/h2>\n

EGFR belongs to the Type I receptor tyrosine kinase family. It includes an extracellular
\nligand-binding domain, a short transmembrane region, and an intracellular domain with tyrosine
\nkinase activity. Although EGFR is present in many normal tissues\u2014especially in the basal layer of
\nsquamous epithelium\u2014overexpression is frequently seen in cancers such as breast, lung, bladder,
\ngastric, esophageal, and head and neck carcinomas.<\/p>\n

How This Antibody Works<\/h2>\n

In immunohistochemistry (IHC), the primary antibody binds specifically to EGFR in tissue sections.
\nA secondary HRP-conjugated antibody is then applied. Using the DAB chromogenic reagent<\/strong>,
\npositive cells develop a clear brown stain located on the cell membrane or in the cytoplasm.<\/p>\n

Key Features<\/h2>\n