{"id":1807,"date":"2025-06-07T12:40:21","date_gmt":"2025-06-07T09:10:21","guid":{"rendered":"https:\/\/fardadazma.com\/en\/?post_type=product&#038;p=1807"},"modified":"2025-11-19T14:23:57","modified_gmt":"2025-11-19T10:53:57","slug":"cytokeratin-hmw-hck-mouse-monoclonal-antibody-6ml","status":"publish","type":"product","link":"https:\/\/fardadazma.com\/en\/product\/cytokeratin-hmw-hck-mouse-monoclonal-antibody-6ml\/","title":{"rendered":"Cytokeratin (HMW) Antibody (Immunohistochemistry)"},"content":{"rendered":"<h2 data-start=\"2410\" data-end=\"2465\">\ud83e\uddea Cytokeratin (HMW) Antibody (Immunohistochemistry)<\/h2>\n<p data-start=\"2467\" data-end=\"2627\"><a href=\"https:\/\/fardadazma.com\/en\/product-category\/pathology\/\">The <strong data-start=\"2471\" data-end=\"2501\">Cytokeratin (HMW) Antibody<\/strong><\/a> is a widely used immunohistochemical marker for identifying <strong data-start=\"2562\" data-end=\"2595\">squamous and ductal epithelia<\/strong> and their related carcinomas.<\/p>\n<p data-start=\"2629\" data-end=\"3000\">This monoclonal antibody (clone 34\u03b2E12) specifically reacts with <strong data-start=\"2694\" data-end=\"2732\">high molecular weight cytokeratins<\/strong> including CK1, CK5, CK10, and CK14, corresponding to molecular weights of 68, 58, 56.5, and 50 kDa. These cytokeratins are typically expressed in <strong data-start=\"2879\" data-end=\"2900\">complex epithelia<\/strong>, making this antibody highly valuable for differential diagnosis of epithelial-origin carcinomas.<\/p>\n<hr data-start=\"3002\" data-end=\"3005\" \/>\n<h3 data-start=\"3007\" data-end=\"3037\">\ud83d\udd2c Features and Benefits<\/h3>\n<ul data-start=\"3038\" data-end=\"3509\">\n<li data-start=\"3038\" data-end=\"3130\">\n<p data-start=\"3040\" data-end=\"3130\"><strong data-start=\"3040\" data-end=\"3071\">Specific epithelial marker:<\/strong> Ideal for detecting squamous and ductal epithelial cells<\/p>\n<\/li>\n<li data-start=\"3131\" data-end=\"3247\">\n<p data-start=\"3133\" data-end=\"3247\"><strong data-start=\"3133\" data-end=\"3158\">Diagnostic precision:<\/strong> Useful in identifying carcinomas of the prostate, breast, and other epithelial tissues<\/p>\n<\/li>\n<li data-start=\"3248\" data-end=\"3342\">\n<p data-start=\"3250\" data-end=\"3342\"><strong data-start=\"3250\" data-end=\"3281\">Clear cytoplasmic staining:<\/strong> Brown staining observed in the cytoplasm of positive cells<\/p>\n<\/li>\n<li data-start=\"3343\" data-end=\"3443\">\n<p data-start=\"3345\" data-end=\"3443\"><strong data-start=\"3345\" data-end=\"3388\">Compatible with standard IHC protocols:<\/strong> Suitable for both clinical and research laboratories<\/p>\n<\/li>\n<li data-start=\"3444\" data-end=\"3509\">\n<p data-start=\"3446\" data-end=\"3509\"><strong data-start=\"3446\" data-end=\"3469\">Stable performance:<\/strong> Long shelf life (18 months) at 2\u20138 \u00b0C<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"3511\" data-end=\"3514\" \/>\n<h3 data-start=\"3516\" data-end=\"3547\">\u2699\ufe0f Principle of the Assay<\/h3>\n<p data-start=\"3548\" data-end=\"3915\">During the IHC process, the Cytokeratin (HMW) antibody binds to its target antigen within the tissue. A secondary antibody conjugated with HRP attaches to the primary antibody, forming the <strong data-start=\"3737\" data-end=\"3769\">antigen\u2013antibody\u2013HRP complex<\/strong>. When DAB chromogen is added, a brown insoluble staining reaction occurs in the cytoplasm of positive cells, confirming cytokeratin expression.<\/p>\n<hr data-start=\"3917\" data-end=\"3920\" \/>\n<h3 data-start=\"3922\" data-end=\"3954\">\ud83d\udca1 Diagnostic Applications<\/h3>\n<ul data-start=\"3955\" data-end=\"4220\">\n<li data-start=\"3955\" data-end=\"4006\">\n<p data-start=\"3957\" data-end=\"4006\">Detection of <strong data-start=\"3970\" data-end=\"4004\">squamous and ductal carcinomas<\/strong><\/p>\n<\/li>\n<li data-start=\"4007\" data-end=\"4061\">\n<p data-start=\"4009\" data-end=\"4061\">Identification of <strong data-start=\"4027\" data-end=\"4059\">complex epithelial neoplasms<\/strong><\/p>\n<\/li>\n<li data-start=\"4062\" data-end=\"4138\">\n<p data-start=\"4064\" data-end=\"4138\">Differential diagnosis of <strong data-start=\"4090\" data-end=\"4112\">prostate carcinoma<\/strong> and other tissue tumors<\/p>\n<\/li>\n<li data-start=\"4139\" data-end=\"4220\">\n<p data-start=\"4141\" data-end=\"4220\">Research on <strong data-start=\"4153\" data-end=\"4183\">HMW cytokeratin expression<\/strong> in pathology and molecular biology<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"4222\" data-end=\"4225\" \/>\n<h3 data-start=\"4227\" data-end=\"4255\">\ud83c\udf10 Fardad Azma Rad Co.<\/h3>\n<p data-start=\"4257\" data-end=\"4658\"><strong data-start=\"4257\" data-end=\"4280\"><a href=\"https:\/\/fardadazma.com\/en\/contact-us\/\">Fardad Azma Rad<\/a> Co.<\/strong>, the <strong data-start=\"4286\" data-end=\"4335\">exclusive representative of<a href=\"https:\/\/fardadazma.com\/en\/talent\/\"> Talent Biomedical<\/a><\/strong> in Iran, supplies high-quality <strong data-start=\"4367\" data-end=\"4402\">immunohistochemistry antibodies<\/strong>, including <strong data-start=\"4414\" data-end=\"4435\">Cytokeratin (HMW)<\/strong>.<br data-start=\"4436\" data-end=\"4439\" \/>With a strong commitment to <strong data-start=\"4467\" data-end=\"4528\">accuracy, quality, and international diagnostic standards<\/strong>, Fardad Azma Rad delivers advanced molecular and histopathological solutions for laboratories and research centers across Iran.<\/p>\n<p><a href=\"https:\/\/fardadazma.com\/wp-content\/uploads\/2025\/10\/CytokeratinHMW-Instruction-for-Use.pdf\"><strong>&#8220;Download Brochure&#8221;<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<table>\n<thead>\n<tr>\n<th>Item<\/th>\n<th>Description<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Product Name<\/strong><\/td>\n<td>Cytokeratin (HMW) Antibody (Immunohistochemistry)<\/td>\n<\/tr>\n<tr>\n<td><strong>Application<\/strong><\/td>\n<td>Immunohistochemical detection of high molecular weight cytokeratins in epithelial tissues<\/td>\n<\/tr>\n<tr>\n<td><strong>Antigen Localization<\/strong><\/td>\n<td>Cytoplasm<\/td>\n<\/tr>\n<tr>\n<td><strong>Sample Type<\/strong><\/td>\n<td>FFPE tissue sections (3\u20135 \u00b5m)<\/td>\n<\/tr>\n<tr>\n<td><strong>Detection Method<\/strong><\/td>\n<td>IHC staining using DAB chromogen<\/td>\n<\/tr>\n<tr>\n<td><strong>Positive Control<\/strong><\/td>\n<td>Prostate tissue<\/td>\n<\/tr>\n<tr>\n<td><strong>Available Volumes<\/strong><\/td>\n<td>0.2 ml, 1 ml, 3 ml, 6 ml, 11 ml<\/td>\n<\/tr>\n<tr>\n<td><strong>Storage Conditions<\/strong><\/td>\n<td>2\u20138 \u00b0C<\/td>\n<\/tr>\n<tr>\n<td><strong>Shelf Life<\/strong><\/td>\n<td>18 months from production date<\/td>\n<\/tr>\n<tr>\n<td><strong>Manufacturer<\/strong><\/td>\n<td>Talent Biomedical Technology Co., Ltd. \u2013 China<\/td>\n<\/tr>\n<tr>\n<td><strong>Exclusive Representative in Iran<\/strong><\/td>\n<td>Fardad Azma Rad Co.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"featured_media":2602,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[27],"product_tag":[1250,1294,883,1182,1295,881,1272,1171,1273,1296],"class_list":{"0":"post-1807","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-pathology","7":"product_tag-6ml-volume","8":"product_tag-cytokeratin-hmw-antibody","9":"product_tag-diagnostic-reagent","10":"product_tag-epithelial-cell-marker","11":"product_tag-hmw-high-molecular-weight-cytokeratin","12":"product_tag-immunohistochemistry-ihc","13":"product_tag-laboratory-antibody","14":"product_tag-mouse-monoclonal-antibody","15":"product_tag-research-reagent","16":"product_tag-tumor-pathology","18":"first","19":"instock","20":"shipping-taxable","21":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - 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