{"id":1786,"date":"2025-06-07T11:18:02","date_gmt":"2025-06-07T07:48:02","guid":{"rendered":"https:\/\/fardadazma.com\/en\/?post_type=product&#038;p=1786"},"modified":"2025-11-19T14:24:53","modified_gmt":"2025-11-19T10:54:53","slug":"mdm2-mouse-monoclonal-antibody-6ml","status":"publish","type":"product","link":"https:\/\/fardadazma.com\/en\/product\/mdm2-mouse-monoclonal-antibody-6ml\/","title":{"rendered":"MDM2 Antibody (Immunohistochemistry)"},"content":{"rendered":"<h2 data-start=\"2220\" data-end=\"2262\">\ud83e\uddea MDM2 Antibody (Immunohistochemistry)<\/h2>\n<p data-start=\"2264\" data-end=\"2641\">The <a href=\"https:\/\/fardadazma.com\/en\/product-category\/pathology\/\"><strong data-start=\"2268\" data-end=\"2285\">MDM2 Antibody<\/strong> <\/a>is a key immunohistochemical marker used for identifying <strong data-start=\"2343\" data-end=\"2400\">well-differentiated and dedifferentiated liposarcomas<\/strong> as well as other tumors with MDM2 gene amplification.<br data-start=\"2454\" data-end=\"2457\" \/>MDM2 is a <strong data-start=\"2467\" data-end=\"2517\">negative regulator of the tumor suppressor p53<\/strong>, involved in controlling the cell cycle and inhibiting apoptosis, thereby contributing to tumor progression and survival.<\/p>\n<p data-start=\"2643\" data-end=\"2810\">Overexpression or gene amplification of MDM2 is observed in a variety of neoplasms, including <strong data-start=\"2737\" data-end=\"2807\">soft tissue sarcomas, osteosarcomas, and certain epithelial tumors<\/strong>.<\/p>\n<hr data-start=\"2812\" data-end=\"2815\" \/>\n<h3 data-start=\"2817\" data-end=\"2847\">\ud83d\udd2c Features and Benefits<\/h3>\n<ul data-start=\"2848\" data-end=\"3213\">\n<li data-start=\"2848\" data-end=\"2934\">\n<p data-start=\"2850\" data-end=\"2934\"><strong data-start=\"2850\" data-end=\"2886\">Specific marker for liposarcoma:<\/strong> Differentiates liposarcoma from benign lipoma<\/p>\n<\/li>\n<li data-start=\"2935\" data-end=\"3018\">\n<p data-start=\"2937\" data-end=\"3018\"><strong data-start=\"2937\" data-end=\"2967\">Distinct nuclear staining:<\/strong> Brown nuclear coloration in positive tumor cells<\/p>\n<\/li>\n<li data-start=\"3019\" data-end=\"3104\">\n<p data-start=\"3021\" data-end=\"3104\"><strong data-start=\"3021\" data-end=\"3050\">Broad diagnostic utility:<\/strong> Effective for soft tissue and bone tumor evaluation<\/p>\n<\/li>\n<li data-start=\"3105\" data-end=\"3151\">\n<p data-start=\"3107\" data-end=\"3151\"><strong data-start=\"3107\" data-end=\"3149\">Compatible with standard IHC protocols<\/strong><\/p>\n<\/li>\n<li data-start=\"3152\" data-end=\"3213\">\n<p data-start=\"3154\" data-end=\"3213\"><strong data-start=\"3154\" data-end=\"3177\">Stable performance:<\/strong> Shelf life of 18 months at 2\u20138 \u00b0C<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"3215\" data-end=\"3218\" \/>\n<h3 data-start=\"3220\" data-end=\"3251\">\u2699\ufe0f Principle of the Assay<\/h3>\n<p data-start=\"3252\" data-end=\"3579\">During the IHC process, MDM2 antibody binds to the nuclear antigen within tumor cells. The HRP-conjugated secondary antibody binds to the primary antibody to form the <strong data-start=\"3419\" data-end=\"3451\">antigen\u2013antibody\u2013HRP complex<\/strong>. Upon addition of DAB chromogen, a brown insoluble stain appears in the nuclei of positive cells, confirming MDM2 expression.<\/p>\n<hr data-start=\"3581\" data-end=\"3584\" \/>\n<h3 data-start=\"3586\" data-end=\"3618\">\ud83d\udca1 Diagnostic Applications<\/h3>\n<ul data-start=\"3619\" data-end=\"3898\">\n<li data-start=\"3619\" data-end=\"3692\">\n<p data-start=\"3621\" data-end=\"3692\">Detection of <strong data-start=\"3634\" data-end=\"3690\">Well-differentiated and Dedifferentiated Liposarcoma<\/strong><\/p>\n<\/li>\n<li data-start=\"3693\" data-end=\"3754\">\n<p data-start=\"3695\" data-end=\"3754\">Differentiation between <strong data-start=\"3719\" data-end=\"3752\">liposarcoma and benign lipoma<\/strong><\/p>\n<\/li>\n<li data-start=\"3755\" data-end=\"3831\">\n<p data-start=\"3757\" data-end=\"3831\">Assessment of <strong data-start=\"3771\" data-end=\"3798\">MDM2 gene amplification<\/strong> in bone and mesenchymal tumors<\/p>\n<\/li>\n<li data-start=\"3832\" data-end=\"3898\">\n<p data-start=\"3834\" data-end=\"3898\">Research related to <strong data-start=\"3854\" data-end=\"3896\">p53 signaling and apoptosis regulation<\/strong><\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"3900\" data-end=\"3903\" \/>\n<h3 data-start=\"3905\" data-end=\"3933\">\ud83c\udf10 Fardad Azma Rad Co.<\/h3>\n<p data-start=\"3935\" data-end=\"4313\"><strong data-start=\"3935\" data-end=\"3958\"><a href=\"https:\/\/fardadazma.com\/en\/contact-us\/\">Fardad Azma Rad<\/a> Co.<\/strong>, the <strong data-start=\"3964\" data-end=\"4013\">exclusive representative of <a href=\"https:\/\/fardadazma.com\/en\/talent\/\">Talent Biomedical<\/a><\/strong> in Iran, provides high-quality <strong data-start=\"4045\" data-end=\"4080\">immunohistochemistry antibodies<\/strong>, including <strong data-start=\"4092\" data-end=\"4100\">MDM2<\/strong>.<br data-start=\"4101\" data-end=\"4104\" \/>Committed to <strong data-start=\"4117\" data-end=\"4172\">precision, innovation, and global quality standards<\/strong>, Fardad Azma Rad delivers advanced molecular and histopathological diagnostic solutions to clinical and research laboratories across Iran.<\/p>\n<p><a href=\"https:\/\/fardadazma.com\/wp-content\/uploads\/2025\/10\/MDM2-Instruction-for-Use.pdf\"><strong>&#8220;Download Brochure&#8221;<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<table>\n<thead>\n<tr>\n<th><strong>Item<\/strong><\/th>\n<th><strong>Description<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Product Name<\/strong><\/td>\n<td>MDM2 Antibody (Immunohistochemistry)<\/td>\n<\/tr>\n<tr>\n<td><strong>Application<\/strong><\/td>\n<td>Immunohistochemical detection of MDM2 antigen in liposarcomas and other tumors<\/td>\n<\/tr>\n<tr>\n<td><strong>Antigen Localization<\/strong><\/td>\n<td>Nucleus<\/td>\n<\/tr>\n<tr>\n<td><strong>Sample Type<\/strong><\/td>\n<td>FFPE tissue sections (3\u20135 \u00b5m)<\/td>\n<\/tr>\n<tr>\n<td><strong>Detection Method<\/strong><\/td>\n<td>IHC staining using DAB chromogen<\/td>\n<\/tr>\n<tr>\n<td><strong>Positive Control<\/strong><\/td>\n<td>Liposarcoma tissue<\/td>\n<\/tr>\n<tr>\n<td><strong>Available Volumes<\/strong><\/td>\n<td>0.2 ml, 1 ml, 3 ml, 6 ml, 11 ml<\/td>\n<\/tr>\n<tr>\n<td><strong>Storage Conditions<\/strong><\/td>\n<td>2\u20138 \u00b0C<\/td>\n<\/tr>\n<tr>\n<td><strong>Shelf Life<\/strong><\/td>\n<td>18 months from production date<\/td>\n<\/tr>\n<tr>\n<td><strong>Manufacturer<\/strong><\/td>\n<td>Talent Biomedical Technology Co., Ltd. \u2013 China<\/td>\n<\/tr>\n<tr>\n<td><strong>Exclusive Representative in Iran<\/strong><\/td>\n<td>Fardad Azma Rad Co.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"featured_media":1787,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[27],"product_tag":[1250,1185,883,881,1272,1279,1171,1280,1273,1281],"class_list":{"0":"post-1786","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-pathology","7":"product_tag-6ml-volume","8":"product_tag-cancer-research","9":"product_tag-diagnostic-reagent","10":"product_tag-immunohistochemistry-ihc","11":"product_tag-laboratory-antibody","12":"product_tag-mdm2-antibody","13":"product_tag-mouse-monoclonal-antibody","14":"product_tag-oncoprotein","15":"product_tag-research-reagent","16":"product_tag-tumor-suppressor-regulator","18":"first","19":"instock","20":"shipping-taxable","21":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - 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