{"id":1679,"date":"2025-05-31T11:00:53","date_gmt":"2025-05-31T07:30:53","guid":{"rendered":"https:\/\/fardadazma.com\/en\/?post_type=product&#038;p=1679"},"modified":"2025-11-26T15:24:47","modified_gmt":"2025-11-26T11:54:47","slug":"mlh1-mouse-monoclonal-antibody-6ml","status":"publish","type":"product","link":"https:\/\/fardadazma.com\/en\/product\/mlh1-mouse-monoclonal-antibody-6ml\/","title":{"rendered":"MLH1 Antibody (Immunohistochemistry)"},"content":{"rendered":"<h1><strong>MLH1 Antibody (Immunohistochemistry)<\/strong><\/h1>\n<p>The <a href=\"https:\/\/fardadazma.com\/en\/product-category\/pathology\/\"><strong>MLH1 Antibody<\/strong><\/a> is an essential immunohistochemical marker used in evaluating the<br \/>\n<strong>Mismatch Repair (MMR) pathway<\/strong>, particularly in the diagnosis of<br \/>\n<strong>colorectal cancer<\/strong> and<br \/>\n<strong>genetic MMR defects<\/strong>.<br \/>\nMLH1 is a critical component of the <strong>MMR system<\/strong>, responsible for recognizing and repairing DNA replication errors to maintain genomic stability.<\/p>\n<p>Loss of <strong>MLH1 expression<\/strong> is a major indicator of<br \/>\n<strong>MMR deficiency<\/strong> and is strongly associated with<br \/>\n<strong>Hereditary Nonpolyposis Colorectal Cancer (HNPCC \/ Lynch Syndrome)<\/strong>.<br \/>\nIHC staining typically shows <strong>brown nuclear staining<\/strong> in positive cells, providing valuable information for both diagnostic and genetic evaluations.<\/p>\n<hr \/>\n<h3>\ud83d\udd2c Features and Benefits MLH1 Antibody<\/h3>\n<ul>\n<li><strong>Key marker for diagnosing colorectal cancer and MSI-related genetic defects<\/strong><\/li>\n<li><strong>Produces distinct brown nuclear staining<\/strong><\/li>\n<li><strong>Useful for identifying Hereditary Nonpolyposis Colorectal Cancer (HNPCC)<\/strong><\/li>\n<li><strong>Compatible with standard IHC staining protocols<\/strong><\/li>\n<li><strong>Excellent stability:<\/strong> 18-month shelf life at 2\u20138 \u00b0C<\/li>\n<\/ul>\n<hr \/>\n<h3>\ud83d\udca1 Diagnostic Applications<\/h3>\n<ul>\n<li>Detection of <strong>colorectal cancer<\/strong> and evaluation of <strong>microsatellite instability (MSI)<\/strong><\/li>\n<li><strong>Genetic analysis of MMR-deficient tumors<\/strong><\/li>\n<li><strong>Microsatellite instability (MSI)<\/strong> testing in suspected hereditary cancers<\/li>\n<li>Identification of <strong>MMR mutations<\/strong> in Lynch syndrome and related genetic disorders<\/li>\n<\/ul>\n<hr \/>\n<h3>\ud83c\udf10 Fardad Azma Rad Co.<\/h3>\n<p><strong><a href=\"https:\/\/fardadazma.com\/en\/contact-us\/\">Fardad Azma Rad Co.<\/a><\/strong>, the<br \/>\n<strong>exclusive representative of <a href=\"https:\/\/fardadazma.com\/en\/talent\/\">Talent Biomedical<\/a><\/strong> in Iran, supplies high-quality<br \/>\n<strong>immunohistochemistry antibodies<\/strong>, including <strong>MLH1<\/strong>.<br \/>\nThe company is dedicated to<br \/>\n<strong>scientific precision, diagnostic excellence, and international standards<\/strong>,<br \/>\nsupporting pathology laboratories and molecular diagnostic centers across Iran.<\/p>\n<p><a href=\"https:\/\/fardadazma.com\/wp-content\/uploads\/2025\/10\/MLH1-Instruction-for-Use.pdf\"><strong>&#8220;Download Brochure&#8221;<\/strong><\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<table>\n<thead>\n<tr>\n<th><strong>Item<\/strong><\/th>\n<th><strong>Description<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Product Name<\/strong><\/td>\n<td>MLH1 Antibody (Immunohistochemistry)<\/td>\n<\/tr>\n<tr>\n<td><strong>Application<\/strong><\/td>\n<td>Immunohistochemical detection of MLH1 in colorectal cancer and MSI testing<\/td>\n<\/tr>\n<tr>\n<td><strong>Antigen Localization<\/strong><\/td>\n<td>Nucleus<\/td>\n<\/tr>\n<tr>\n<td><strong>Sample Type<\/strong><\/td>\n<td>FFPE tissue sections (3\u20135 \u00b5m)<\/td>\n<\/tr>\n<tr>\n<td><strong>Detection Method<\/strong><\/td>\n<td>IHC staining using DAB chromogen<\/td>\n<\/tr>\n<tr>\n<td><strong>Positive Control<\/strong><\/td>\n<td>Colorectal cancer tissue<\/td>\n<\/tr>\n<tr>\n<td><strong>Available Volumes<\/strong><\/td>\n<td>0.2 ml, 1 ml, 3 ml, 6 ml, 11 ml<\/td>\n<\/tr>\n<tr>\n<td><strong>Storage Conditions<\/strong><\/td>\n<td>2\u20138 \u00b0C<\/td>\n<\/tr>\n<tr>\n<td><strong>Shelf Life<\/strong><\/td>\n<td>18 months from production date<\/td>\n<\/tr>\n<tr>\n<td><strong>Manufacturer<\/strong><\/td>\n<td>Talent Biomedical Technology Co., Ltd. \u2013 China<\/td>\n<\/tr>\n<tr>\n<td><strong>Exclusive Representative in Iran<\/strong><\/td>\n<td>Fardad Azma Rad Co.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"featured_media":1680,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[27],"product_tag":[1051,1087,1091,1093,1090,1058,1092,1086,1088,1089],"class_list":{"0":"post-1679","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-pathology","7":"product_tag-6ml-antibody-vial","8":"product_tag-anti-mlh1-mouse-antibody","9":"product_tag-cancer-research-antibody","10":"product_tag-colorectal-cancer-marker","11":"product_tag-dna-mismatch-repair-marker","12":"product_tag-immunohistochemistry-antibody","13":"product_tag-lynch-syndrome-marker","14":"product_tag-mlh1-mouse-monoclonal-antibody","15":"product_tag-monoclonal-mlh1-antibody","16":"product_tag-mouse-monoclonal-antibody-for-mlh1","18":"first","19":"instock","20":"shipping-taxable","21":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 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