{"id":1623,"date":"2025-05-27T11:15:42","date_gmt":"2025-05-27T07:45:42","guid":{"rendered":"https:\/\/fardadazma.com\/en\/?post_type=product&#038;p=1623"},"modified":"2025-11-27T10:48:38","modified_gmt":"2025-11-27T07:18:38","slug":"p53-antibody-reagent-for-immunohistochemistry","status":"publish","type":"product","link":"https:\/\/fardadazma.com\/en\/product\/p53-antibody-reagent-for-immunohistochemistry\/","title":{"rendered":"p53 Antibody (Immunohistochemistry)"},"content":{"rendered":"<h2 data-start=\"1897\" data-end=\"1944\"><strong data-start=\"1905\" data-end=\"1944\">p53 Antibody (Immunohistochemistry)<\/strong><\/h2>\n<p data-start=\"1946\" data-end=\"2317\">The <a href=\"https:\/\/fardadazma.com\/en\/product-category\/pathology\/\"><strong data-start=\"1950\" data-end=\"1966\">p53 Antibody<\/strong> <\/a>is one of the most widely used tumor markers in molecular pathology and plays a crucial role in the <strong data-start=\"2067\" data-end=\"2118\">diagnosis and prognosis of various malignancies<\/strong>.<br data-start=\"2119\" data-end=\"2122\" \/><strong data-start=\"2122\" data-end=\"2129\">p53<\/strong>, also known as <strong data-start=\"2145\" data-end=\"2172\">Tumor Protein 53 (TP53)<\/strong>, is a <strong data-start=\"2179\" data-end=\"2224\">tumor suppressor and transcription factor<\/strong> that regulates <strong data-start=\"2240\" data-end=\"2288\">DNA repair, cell cycle arrest, and apoptosis<\/strong> in response to DNA damage.<\/p>\n<p data-start=\"2319\" data-end=\"2598\">Mutations in the <strong data-start=\"2336\" data-end=\"2348\">p53 gene<\/strong> lead to the loss of its tumor-suppressive functions and are associated with many cancers, including <strong data-start=\"2449\" data-end=\"2502\">breast, lung, colon, bladder, ovary, and melanoma<\/strong>.<br data-start=\"2503\" data-end=\"2506\" \/>In immunohistochemistry, p53 typically shows <strong data-start=\"2551\" data-end=\"2577\">brown nuclear staining<\/strong> in positive cells.<\/p>\n<hr data-start=\"2600\" data-end=\"2603\" \/>\n<h3 data-start=\"2605\" data-end=\"2635\">\ud83d\udd2c Features and Benefits p53 Antibody<\/h3>\n<ul data-start=\"2636\" data-end=\"2932\">\n<li data-start=\"2636\" data-end=\"2692\">\n<p data-start=\"2638\" data-end=\"2692\"><strong data-start=\"2638\" data-end=\"2690\">Standard marker for detecting p53 gene mutations<\/strong><\/p>\n<\/li>\n<li data-start=\"2693\" data-end=\"2762\">\n<p data-start=\"2695\" data-end=\"2762\"><strong data-start=\"2695\" data-end=\"2760\">Applicable to both epithelial and non-epithelial malignancies<\/strong><\/p>\n<\/li>\n<li data-start=\"2763\" data-end=\"2810\">\n<p data-start=\"2765\" data-end=\"2810\"><strong data-start=\"2765\" data-end=\"2808\">Distinct brown nuclear staining pattern<\/strong><\/p>\n<\/li>\n<li data-start=\"2811\" data-end=\"2873\">\n<p data-start=\"2813\" data-end=\"2873\"><strong data-start=\"2813\" data-end=\"2871\">Compatible with FFPE tissues and DAB chromogen systems<\/strong><\/p>\n<\/li>\n<li data-start=\"2874\" data-end=\"2932\">\n<p data-start=\"2876\" data-end=\"2932\"><strong data-start=\"2876\" data-end=\"2900\">Excellent stability:<\/strong> 18-month shelf life at 2\u20138 \u00b0C<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"2934\" data-end=\"2937\" \/>\n<h3 data-start=\"2939\" data-end=\"2971\">\ud83d\udca1 Diagnostic Applications<\/h3>\n<ul data-start=\"2972\" data-end=\"3235\">\n<li data-start=\"2972\" data-end=\"3033\">\n<p data-start=\"2974\" data-end=\"3033\">Detection of <strong data-start=\"2987\" data-end=\"3021\">p53 overexpression or mutation<\/strong> in tumors<\/p>\n<\/li>\n<li data-start=\"3034\" data-end=\"3110\">\n<p data-start=\"3036\" data-end=\"3110\">Diagnosis of <strong data-start=\"3049\" data-end=\"3108\">breast, ovarian, bladder, lung, colon, and skin cancers<\/strong><\/p>\n<\/li>\n<li data-start=\"3111\" data-end=\"3171\">\n<p data-start=\"3113\" data-end=\"3171\">Evaluation of <strong data-start=\"3127\" data-end=\"3169\">tumor prognosis and treatment response<\/strong><\/p>\n<\/li>\n<li data-start=\"3172\" data-end=\"3235\">\n<p data-start=\"3174\" data-end=\"3235\">Research on <strong data-start=\"3186\" data-end=\"3233\">tumor suppression and cell cycle regulation<\/strong><\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"3237\" data-end=\"3240\" \/>\n<h3 data-start=\"3242\" data-end=\"3270\">\ud83c\udf10 Fardad Azma Rad Co.<\/h3>\n<p data-start=\"3272\" data-end=\"3627\"><strong data-start=\"3272\" data-end=\"3295\"><a href=\"https:\/\/fardadazma.com\/en\/about\/\">Fardad Azma Rad<\/a> Co.<\/strong>, the <strong data-start=\"3301\" data-end=\"3350\">exclusive representative of <a href=\"https:\/\/fardadazma.com\/en\/talent\/\">Talent Biomedical<\/a><\/strong> in Iran, supplies high-quality <strong data-start=\"3382\" data-end=\"3417\">immunohistochemistry antibodies<\/strong>, including <strong data-start=\"3429\" data-end=\"3436\">p53<\/strong>.<br data-start=\"3437\" data-end=\"3440\" \/>With a commitment to <strong data-start=\"3461\" data-end=\"3538\">scientific precision, diagnostic reliability, and international standards<\/strong>, Fardad Azma Rad supports pathology and molecular diagnostic laboratories across Iran.<\/p>\n<p><a href=\"https:\/\/fardadazma.com\/wp-content\/uploads\/2025\/10\/p53-Instruction-for-Use.pdf\"><strong>&#8220;Download Brochure&#8221;<\/strong><\/a><\/p>\n<p data-start=\"1900\" data-end=\"1923\">\n","protected":false},"excerpt":{"rendered":"<table>\n<thead>\n<tr>\n<th><strong>Item<\/strong><\/th>\n<th><strong>Description<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Product Name<\/strong><\/td>\n<td>p53 Antibody (Immunohistochemistry)<\/td>\n<\/tr>\n<tr>\n<td><strong>Application<\/strong><\/td>\n<td>Immunohistochemical detection of p53 expression and mutations in various cancers<\/td>\n<\/tr>\n<tr>\n<td><strong>Antigen Localization<\/strong><\/td>\n<td>Nucleus<\/td>\n<\/tr>\n<tr>\n<td><strong>Sample Type<\/strong><\/td>\n<td>FFPE tissue sections (3\u20135 \u00b5m)<\/td>\n<\/tr>\n<tr>\n<td><strong>Detection Method<\/strong><\/td>\n<td>IHC staining using DAB chromogen<\/td>\n<\/tr>\n<tr>\n<td><strong>Positive Control<\/strong><\/td>\n<td>Ovarian cancer tissue<\/td>\n<\/tr>\n<tr>\n<td><strong>Available Volumes<\/strong><\/td>\n<td>0.2 ml, 1 ml, 3 ml, 6 ml, 11 ml<\/td>\n<\/tr>\n<tr>\n<td><strong>Storage Conditions<\/strong><\/td>\n<td>2\u20138 \u00b0C<\/td>\n<\/tr>\n<tr>\n<td><strong>Shelf Life<\/strong><\/td>\n<td>18 months from production date<\/td>\n<\/tr>\n<tr>\n<td><strong>Manufacturer<\/strong><\/td>\n<td>Talent Biomedical Technology Co., Ltd. \u2013 China<\/td>\n<\/tr>\n<tr>\n<td><strong>Exclusive Representative in Iran<\/strong><\/td>\n<td>Fardad Azma Rad Co.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"featured_media":1624,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[27],"product_tag":[949,927,936,952,951,950,954,945,953],"class_list":{"0":"post-1623","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-pathology","7":"product_tag-cancer-diagnostic-antibody","8":"product_tag-dab-chromogen-ihc","9":"product_tag-ffpe-tissue-antibody","10":"product_tag-immunohistochemistry-p53","11":"product_tag-mutation-marker","12":"product_tag-ovarian-cancer-marker","13":"product_tag-p53-antibody","14":"product_tag-tumor-suppressor-marker","15":"product_tag-tumour-protein-53","17":"first","18":"instock","19":"shipping-taxable","20":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>p53 Antibody (Immunohistochemistry) - 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