{"id":1620,"date":"2025-05-27T11:01:29","date_gmt":"2025-05-27T07:31:29","guid":{"rendered":"https:\/\/fardadazma.com\/en\/?post_type=product&#038;p=1620"},"modified":"2025-11-27T10:48:41","modified_gmt":"2025-11-27T07:18:41","slug":"p16-antibody-reagent-for-immunohistochemistry","status":"publish","type":"product","link":"https:\/\/fardadazma.com\/en\/product\/p16-antibody-reagent-for-immunohistochemistry\/","title":{"rendered":"p16 Antibody (Immunohistochemistry)"},"content":{"rendered":"<h2 data-start=\"1978\" data-end=\"2025\"><strong data-start=\"1986\" data-end=\"2025\">p16 Antibody (Immunohistochemistry)<\/strong><\/h2>\n<p data-start=\"2027\" data-end=\"2483\">The <a href=\"https:\/\/fardadazma.com\/en\/product-category\/pathology\/\"><strong data-start=\"2031\" data-end=\"2058\">p16 (p16INK4A) Antibody<\/strong><\/a> is a key immunohistochemical marker widely used for the <strong data-start=\"2115\" data-end=\"2156\">detection of HPV-associated neoplasms<\/strong> and other malignancies.<br data-start=\"2180\" data-end=\"2183\" \/><strong data-start=\"2183\" data-end=\"2190\">p16<\/strong> is a <strong data-start=\"2196\" data-end=\"2239\">cyclin-dependent kinase (CDK) inhibitor<\/strong> that regulates the cell cycle by preventing the <strong data-start=\"2288\" data-end=\"2316\">G1 to S phase transition<\/strong> through the inhibition of the <strong data-start=\"2347\" data-end=\"2374\">Cyclin D\u2013CDK4\/6 pathway<\/strong>.<br data-start=\"2375\" data-end=\"2378\" \/>This mechanism suppresses abnormal cell proliferation, making <strong data-start=\"2440\" data-end=\"2480\">p16 a vital tumor suppressor protein<\/strong>.<\/p>\n<p data-start=\"2485\" data-end=\"2745\">Overexpression of p16 is commonly observed in <strong data-start=\"2531\" data-end=\"2554\">cervical carcinomas<\/strong>, as well as <strong data-start=\"2567\" data-end=\"2638\">head and neck cancers, melanomas, gliomas, lymphomas, and leukemias<\/strong>.<br data-start=\"2639\" data-end=\"2642\" \/>In IHC staining, p16 typically exhibits <strong data-start=\"2682\" data-end=\"2724\">brown nuclear and cytoplasmic staining<\/strong> in positive cells.<\/p>\n<hr data-start=\"2747\" data-end=\"2750\" \/>\n<h3 data-start=\"2752\" data-end=\"2782\">\ud83d\udd2c Features and Benefits<\/h3>\n<ul data-start=\"2783\" data-end=\"3091\">\n<li data-start=\"2783\" data-end=\"2830\">\n<p data-start=\"2785\" data-end=\"2830\"><strong data-start=\"2785\" data-end=\"2828\">Sensitive marker for HPV-related tumors<\/strong><\/p>\n<\/li>\n<li data-start=\"2831\" data-end=\"2886\">\n<p data-start=\"2833\" data-end=\"2886\"><strong data-start=\"2833\" data-end=\"2884\">Distinct brown nuclear and cytoplasmic staining<\/strong><\/p>\n<\/li>\n<li data-start=\"2887\" data-end=\"2971\">\n<p data-start=\"2889\" data-end=\"2971\"><strong data-start=\"2889\" data-end=\"2969\">Applicable for cancers of the cervix, esophagus, pancreas, lung, and bladder<\/strong><\/p>\n<\/li>\n<li data-start=\"2972\" data-end=\"3032\">\n<p data-start=\"2974\" data-end=\"3032\"><strong data-start=\"2974\" data-end=\"3030\">Compatible with FFPE tissue and DAB chromogen system<\/strong><\/p>\n<\/li>\n<li data-start=\"3033\" data-end=\"3091\">\n<p data-start=\"3035\" data-end=\"3091\"><strong data-start=\"3035\" data-end=\"3059\">Excellent stability:<\/strong> 18-month shelf life at 2\u20138 \u00b0C<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"3093\" data-end=\"3096\" \/>\n<h3 data-start=\"3098\" data-end=\"3130\">\ud83d\udca1 Diagnostic Applications<\/h3>\n<ul data-start=\"3131\" data-end=\"3401\">\n<li data-start=\"3131\" data-end=\"3186\">\n<p data-start=\"3133\" data-end=\"3186\">Detection of <strong data-start=\"3146\" data-end=\"3184\">HPV-associated cervical carcinomas<\/strong><\/p>\n<\/li>\n<li data-start=\"3187\" data-end=\"3253\">\n<p data-start=\"3189\" data-end=\"3253\">Identification of <strong data-start=\"3207\" data-end=\"3251\">melanoma, glioma, and lymphoid neoplasms<\/strong><\/p>\n<\/li>\n<li data-start=\"3254\" data-end=\"3337\">\n<p data-start=\"3256\" data-end=\"3337\">Evaluation of <strong data-start=\"3270\" data-end=\"3335\">esophageal, pancreatic, hepatic, and biliary tract carcinomas<\/strong><\/p>\n<\/li>\n<li data-start=\"3338\" data-end=\"3401\">\n<p data-start=\"3340\" data-end=\"3401\">Research on <strong data-start=\"3352\" data-end=\"3399\">cell cycle regulation and viral oncogenesis<\/strong><\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"3403\" data-end=\"3406\" \/>\n<h3 data-start=\"3408\" data-end=\"3436\">\ud83c\udf10 Fardad Azma Rad Co.<\/h3>\n<p data-start=\"3438\" data-end=\"3827\"><strong data-start=\"3438\" data-end=\"3461\"><a href=\"https:\/\/fardadazma.com\/en\/about\/\">Fardad Azma Rad<\/a> Co.<\/strong>, the <strong data-start=\"3467\" data-end=\"3516\">exclusive representative of <a href=\"https:\/\/fardadazma.com\/en\/talent\/\">Talent Biomedical<\/a><\/strong> in Iran, supplies high-quality <strong data-start=\"3548\" data-end=\"3583\">immunohistochemistry antibodies<\/strong>, including <strong data-start=\"3595\" data-end=\"3602\">p16<\/strong>.<br data-start=\"3603\" data-end=\"3606\" \/>With a strong commitment to <strong data-start=\"3634\" data-end=\"3710\">scientific accuracy, diagnostic reliability, and international standards<\/strong>, Fardad Azma Rad provides comprehensive diagnostic solutions for pathology and molecular laboratories across Iran.<\/p>\n<p><a href=\"https:\/\/fardadazma.com\/wp-content\/uploads\/2025\/10\/p16-Instruction-for-Use.pdf\"><strong>&#8220;Download Brochure&#8221;<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<table>\n<thead>\n<tr>\n<th><strong>Item<\/strong><\/th>\n<th><strong>Description<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Product Name<\/strong><\/td>\n<td>p16 Antibody (Immunohistochemistry)<\/td>\n<\/tr>\n<tr>\n<td><strong>Application<\/strong><\/td>\n<td>Immunohistochemical detection of HPV-related and epithelial neoplasms<\/td>\n<\/tr>\n<tr>\n<td><strong>Antigen Localization<\/strong><\/td>\n<td>Nucleus \/ Cytoplasm<\/td>\n<\/tr>\n<tr>\n<td><strong>Sample Type<\/strong><\/td>\n<td>FFPE tissue sections (3\u20135 \u00b5m)<\/td>\n<\/tr>\n<tr>\n<td><strong>Detection Method<\/strong><\/td>\n<td>IHC staining using DAB chromogen<\/td>\n<\/tr>\n<tr>\n<td><strong>Positive Control<\/strong><\/td>\n<td>Cervical carcinoma tissue<\/td>\n<\/tr>\n<tr>\n<td><strong>Available Volumes<\/strong><\/td>\n<td>0.2 ml, 1 ml, 3 ml, 6 ml, 11 ml<\/td>\n<\/tr>\n<tr>\n<td><strong>Storage Conditions<\/strong><\/td>\n<td>2\u20138 \u00b0C<\/td>\n<\/tr>\n<tr>\n<td><strong>Shelf Life<\/strong><\/td>\n<td>18 months from production date<\/td>\n<\/tr>\n<tr>\n<td><strong>Manufacturer<\/strong><\/td>\n<td>Talent Biomedical Technology Co., Ltd. \u2013 China<\/td>\n<\/tr>\n<tr>\n<td><strong>Exclusive Representative in Iran<\/strong><\/td>\n<td>Fardad Azma Rad Co.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"featured_media":1621,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[27],"product_tag":[949,947,927,936,948,946,943,944,945],"class_list":{"0":"post-1620","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-pathology","7":"product_tag-cancer-diagnostic-antibody","8":"product_tag-cervical-cancer-marker","9":"product_tag-dab-chromogen-ihc","10":"product_tag-ffpe-tissue-antibody","11":"product_tag-head-and-neck-cancer-marker","12":"product_tag-immunohistochemistry-p16","13":"product_tag-p16-antibody","14":"product_tag-p16ink4a-ihc-antibody","15":"product_tag-tumor-suppressor-marker","17":"first","18":"instock","19":"shipping-taxable","20":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>p16 Antibody 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production date   Manufacturer Talent Biomedical Technology Co., Ltd. \u2013 China   Exclusive Representative in Iran Fardad Azma Rad Co.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/fardadazma.com\/en\/product\/p16-antibody-reagent-for-immunohistochemistry\/\" \/>\n<meta property=\"og:site_name\" content=\"Fardadazma\" \/>\n<meta property=\"article:modified_time\" content=\"2025-11-27T07:18:41+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/fardadazma.com\/en\/wp-content\/uploads\/sites\/2\/2025\/05\/2812eb99aa52a855df25efb574ac4488_medium.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"505\" \/>\n\t<meta property=\"og:image:height\" content=\"505\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" 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