{"id":1611,"date":"2025-05-27T09:51:53","date_gmt":"2025-05-27T06:21:53","guid":{"rendered":"https:\/\/fardadazma.com\/en\/?post_type=product&#038;p=1611"},"modified":"2025-11-27T10:48:49","modified_gmt":"2025-11-27T07:18:49","slug":"cd117-antibody-reagent-for-immunohistochemistry","status":"publish","type":"product","link":"https:\/\/fardadazma.com\/en\/product\/cd117-antibody-reagent-for-immunohistochemistry\/","title":{"rendered":"CD117 (c-Kit) Antibody (Immunohistochemistry)"},"content":{"rendered":"<h2 data-start=\"1906\" data-end=\"1963\"><strong data-start=\"1914\" data-end=\"1963\">CD117 (c-Kit) Antibody (Immunohistochemistry)<\/strong><\/h2>\n<p data-start=\"1965\" data-end=\"2424\">The <a href=\"https:\/\/fardadazma.com\/en\/product-category\/pathology\/\"><strong data-start=\"1969\" data-end=\"1995\">CD117 (c-Kit) Antibody<\/strong><\/a> is an essential immunohistochemical marker used primarily in the diagnosis of <strong data-start=\"2074\" data-end=\"2117\">Gastrointestinal Stromal Tumors (GISTs)<\/strong> and other <strong data-start=\"2128\" data-end=\"2158\">c-Kit\u2013expressing neoplasms<\/strong>.<br data-start=\"2159\" data-end=\"2162\" \/><strong data-start=\"2162\" data-end=\"2171\">CD117<\/strong> is the gene product of the <strong data-start=\"2199\" data-end=\"2223\">c-kit proto-oncogene<\/strong> and functions as a <strong data-start=\"2243\" data-end=\"2285\">transmembrane tyrosine kinase receptor<\/strong>. It interacts with its ligand, <strong data-start=\"2317\" data-end=\"2343\">stem cell factor (SCF)<\/strong>, and plays vital roles in <strong data-start=\"2370\" data-end=\"2421\">hematopoiesis, melanogenesis, and gametogenesis<\/strong>.<\/p>\n<p data-start=\"2426\" data-end=\"2729\">This marker is expressed on <strong data-start=\"2454\" data-end=\"2547\">endothelial cells, mast cells, megakaryocytes, hematopoietic stem cells, and melanoblasts<\/strong>.<br data-start=\"2548\" data-end=\"2551\" \/>In IHC staining, CD117 shows <strong data-start=\"2580\" data-end=\"2636\">distinct brown cytoplasmic and membranous positivity<\/strong>, providing strong diagnostic value for <strong data-start=\"2676\" data-end=\"2726\">GIST, mast cell disease, and myeloid neoplasms<\/strong>.<\/p>\n<hr data-start=\"2731\" data-end=\"2734\" \/>\n<h3 data-start=\"2736\" data-end=\"2766\">\ud83d\udd2c Features and Benefits CD117 (c-Kit) Antibody<\/h3>\n<ul data-start=\"2767\" data-end=\"3076\">\n<li data-start=\"2767\" data-end=\"2835\">\n<p data-start=\"2769\" data-end=\"2835\"><strong data-start=\"2769\" data-end=\"2833\">Specific marker for GIST, mast cells, and soft tissue tumors<\/strong><\/p>\n<\/li>\n<li data-start=\"2836\" data-end=\"2899\">\n<p data-start=\"2838\" data-end=\"2899\"><strong data-start=\"2838\" data-end=\"2897\">Clear membranous and cytoplasmic brown staining pattern<\/strong><\/p>\n<\/li>\n<li data-start=\"2900\" data-end=\"2964\">\n<p data-start=\"2902\" data-end=\"2964\"><strong data-start=\"2902\" data-end=\"2962\">Useful for differentiating stromal and myeloid neoplasms<\/strong><\/p>\n<\/li>\n<li data-start=\"2965\" data-end=\"3027\">\n<p data-start=\"2967\" data-end=\"3027\"><strong data-start=\"2967\" data-end=\"3025\">Compatible with FFPE samples and DAB detection systems<\/strong><\/p>\n<\/li>\n<li data-start=\"3028\" data-end=\"3076\">\n<p data-start=\"3030\" data-end=\"3076\"><strong data-start=\"3030\" data-end=\"3054\">Excellent stability:<\/strong> 18 months at 2\u20138 \u00b0C<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"3078\" data-end=\"3081\" \/>\n<h3 data-start=\"3083\" data-end=\"3115\">\ud83d\udca1 Diagnostic Applications<\/h3>\n<ul data-start=\"3116\" data-end=\"3371\">\n<li data-start=\"3116\" data-end=\"3174\">\n<p data-start=\"3118\" data-end=\"3174\">Detection of <strong data-start=\"3131\" data-end=\"3172\">Gastrointestinal Stromal Tumor (GIST)<\/strong><\/p>\n<\/li>\n<li data-start=\"3175\" data-end=\"3251\">\n<p data-start=\"3177\" data-end=\"3251\">Identification of <strong data-start=\"3195\" data-end=\"3249\">Mastocytosis and hematopoietic stem cell neoplasms<\/strong><\/p>\n<\/li>\n<li data-start=\"3252\" data-end=\"3309\">\n<p data-start=\"3254\" data-end=\"3309\">Differentiation of <strong data-start=\"3273\" data-end=\"3307\">soft tissue and myeloid tumors<\/strong><\/p>\n<\/li>\n<li data-start=\"3310\" data-end=\"3371\">\n<p data-start=\"3312\" data-end=\"3371\">Research on <strong data-start=\"3324\" data-end=\"3369\">tyrosine kinase signaling and oncogenesis<\/strong><\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"3373\" data-end=\"3376\" \/>\n<h3 data-start=\"3378\" data-end=\"3406\">\ud83c\udf10 Fardad Azma Rad Co.<\/h3>\n<p data-start=\"3408\" data-end=\"3759\"><strong data-start=\"3408\" data-end=\"3431\"><a href=\"https:\/\/fardadazma.com\/en\/about\/\">Fardad Azma Rad<\/a> Co.<\/strong>, the <strong data-start=\"3437\" data-end=\"3486\">exclusive representative of <a href=\"https:\/\/fardadazma.com\/en\/talent\/\">Talent Biomedical<\/a><\/strong> in Iran, provides high-quality <strong data-start=\"3518\" data-end=\"3553\">immunohistochemistry antibodies<\/strong>, including <strong data-start=\"3565\" data-end=\"3582\">CD117 (c-Kit)<\/strong>.<br data-start=\"3583\" data-end=\"3586\" \/>With a commitment to <strong data-start=\"3607\" data-end=\"3677\">diagnostic precision, product quality, and international standards<\/strong>, Fardad Azma Rad supports pathology and molecular laboratories throughout Iran.<\/p>\n<p><a href=\"https:\/\/fardadazma.com\/wp-content\/uploads\/2025\/10\/CD117-Instruction-for-Use.pdf\"><strong>&#8220;Download Brochure&#8221;<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<table>\n<thead>\n<tr>\n<th><strong>Item<\/strong><\/th>\n<th><strong>Description<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Product Name<\/strong><\/td>\n<td>CD117 (c-Kit) Antibody (Immunohistochemistry)<\/td>\n<\/tr>\n<tr>\n<td><strong>Application<\/strong><\/td>\n<td>Immunohistochemical detection of c-Kit expression in GIST and related tumors<\/td>\n<\/tr>\n<tr>\n<td><strong>Antigen Localization<\/strong><\/td>\n<td>Cytoplasm \/ Membrane<\/td>\n<\/tr>\n<tr>\n<td><strong>Sample Type<\/strong><\/td>\n<td>FFPE tissue sections (3\u20135 \u00b5m)<\/td>\n<\/tr>\n<tr>\n<td><strong>Detection Method<\/strong><\/td>\n<td>IHC staining using DAB chromogen<\/td>\n<\/tr>\n<tr>\n<td><strong>Positive Control<\/strong><\/td>\n<td>GIST tissue<\/td>\n<\/tr>\n<tr>\n<td><strong>Available Volumes<\/strong><\/td>\n<td>0.2 ml, 1 ml, 3 ml, 6 ml, 11 ml<\/td>\n<\/tr>\n<tr>\n<td><strong>Storage Conditions<\/strong><\/td>\n<td>2\u20138 \u00b0C<\/td>\n<\/tr>\n<tr>\n<td><strong>Shelf Life<\/strong><\/td>\n<td>18 months from production date<\/td>\n<\/tr>\n<tr>\n<td><strong>Manufacturer<\/strong><\/td>\n<td>Talent Biomedical Technology Co., Ltd. \u2013 China<\/td>\n<\/tr>\n<tr>\n<td><strong>Exclusive Representative in Iran<\/strong><\/td>\n<td>Fardad Azma Rad Co.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"featured_media":1613,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[27],"product_tag":[920,919,927,928,923,925,922,926,921,924],"class_list":{"0":"post-1611","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-pathology","7":"product_tag-c-kit-ihc-antibody","8":"product_tag-cd117-antibody","9":"product_tag-dab-chromogen-ihc","10":"product_tag-diagnostic-antibody-reagent","11":"product_tag-gastrointestinal-stromal-tumor-gist-diagnosis","12":"product_tag-hematopoiesis-marker","13":"product_tag-ihc-antibody-for-ffpe-tissue","14":"product_tag-immunohistochemical-detection","15":"product_tag-immunohistochemistry-cd117","16":"product_tag-stem-cell-factor-receptor-detection","18":"first","19":"instock","20":"shipping-taxable","21":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - 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0.2 ml, 1 ml, 3 ml, 6 ml, 11 ml   Storage Conditions 2\u20138 \u00b0C   Shelf Life 18 months from production date   Manufacturer Talent Biomedical Technology Co., Ltd. \u2013 China   Exclusive Representative in Iran Fardad Azma Rad Co.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/fardadazma.com\/en\/product\/cd117-antibody-reagent-for-immunohistochemistry\/\" \/>\n<meta property=\"og:site_name\" content=\"Fardadazma\" \/>\n<meta property=\"article:modified_time\" content=\"2025-11-27T07:18:49+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/fardadazma.com\/en\/wp-content\/uploads\/sites\/2\/2025\/05\/86a9198c72f6e7529f2001e9bb049bac_medium.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"550\" \/>\n\t<meta property=\"og:image:height\" content=\"550\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta 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