{"id":1601,"date":"2025-05-26T15:17:15","date_gmt":"2025-05-26T11:47:15","guid":{"rendered":"https:\/\/fardadazma.com\/en\/?post_type=product&#038;p=1601"},"modified":"2025-11-27T10:48:56","modified_gmt":"2025-11-27T07:18:56","slug":"dog-1-mouse-monoclonal-antibody-6ml","status":"publish","type":"product","link":"https:\/\/fardadazma.com\/en\/product\/dog-1-mouse-monoclonal-antibody-6ml\/","title":{"rendered":"DOG-1 Antibody (Immunohistochemistry)"},"content":{"rendered":"<h2 data-start=\"1817\" data-end=\"1866\"><strong data-start=\"1825\" data-end=\"1866\">DOG-1 Antibody (Immunohistochemistry)<\/strong><\/h2>\n<p data-start=\"1868\" data-end=\"2306\">The <a href=\"https:\/\/fardadazma.com\/en\/product-category\/pathology\/\"><strong data-start=\"1872\" data-end=\"1890\">DOG-1 Antibody<\/strong> <\/a>is one of the most sensitive and specific immunohistochemical markers for diagnosing <strong data-start=\"1976\" data-end=\"2019\">Gastrointestinal Stromal Tumors (GISTs)<\/strong>.<br data-start=\"2020\" data-end=\"2023\" \/>The <strong data-start=\"2027\" data-end=\"2041\">DOG-1 gene<\/strong>, located on <strong data-start=\"2054\" data-end=\"2074\">chromosome 11q13<\/strong>, encodes a protein with <strong data-start=\"2099\" data-end=\"2130\">eight transmembrane domains<\/strong> selectively expressed in GIST cells.<br data-start=\"2167\" data-end=\"2170\" \/>Unlike CD117 (c-Kit), DOG-1 remains <strong data-start=\"2206\" data-end=\"2247\">positive even in CD117-negative GISTs<\/strong>, making it a superior marker for detecting these tumors.<\/p>\n<p data-start=\"2308\" data-end=\"2494\">In IHC staining, DOG-1 exhibits <strong data-start=\"2340\" data-end=\"2385\">brown membranous and cytoplasmic staining<\/strong>, confirming its diagnostic value in differentiating GIST from other <strong data-start=\"2454\" data-end=\"2491\">soft tissue and epithelial tumors<\/strong>.<\/p>\n<hr data-start=\"2496\" data-end=\"2499\" \/>\n<h3 data-start=\"2501\" data-end=\"2531\">\ud83d\udd2c Features and Benefits DOG-1 Antibody<\/h3>\n<ul data-start=\"2532\" data-end=\"2813\">\n<li data-start=\"2532\" data-end=\"2585\">\n<p data-start=\"2534\" data-end=\"2585\"><strong data-start=\"2534\" data-end=\"2583\">Highly specific and sensitive marker for GIST<\/strong><\/p>\n<\/li>\n<li data-start=\"2586\" data-end=\"2631\">\n<p data-start=\"2588\" data-end=\"2631\"><strong data-start=\"2588\" data-end=\"2629\">Positive even in CD117-negative GISTs<\/strong><\/p>\n<\/li>\n<li data-start=\"2632\" data-end=\"2691\">\n<p data-start=\"2634\" data-end=\"2691\"><strong data-start=\"2634\" data-end=\"2689\">Clear brown membranous\/cytoplasmic staining pattern<\/strong><\/p>\n<\/li>\n<li data-start=\"2692\" data-end=\"2754\">\n<p data-start=\"2694\" data-end=\"2754\"><strong data-start=\"2694\" data-end=\"2752\">Compatible with FFPE tissues and DAB detection systems<\/strong><\/p>\n<\/li>\n<li data-start=\"2755\" data-end=\"2813\">\n<p data-start=\"2757\" data-end=\"2813\"><strong data-start=\"2757\" data-end=\"2781\">Excellent stability:<\/strong> 18-month shelf life at 2\u20138 \u00b0C<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"2815\" data-end=\"2818\" \/>\n<h3 data-start=\"2820\" data-end=\"2852\">\ud83d\udca1 Diagnostic Applications<\/h3>\n<ul data-start=\"2853\" data-end=\"3060\">\n<li data-start=\"2853\" data-end=\"2913\">\n<p data-start=\"2855\" data-end=\"2913\">Detection of <strong data-start=\"2868\" data-end=\"2911\">Gastrointestinal Stromal Tumors (GISTs)<\/strong><\/p>\n<\/li>\n<li data-start=\"2914\" data-end=\"2994\">\n<p data-start=\"2916\" data-end=\"2994\">Differentiation from <strong data-start=\"2937\" data-end=\"2992\">leiomyoma, schwannoma, and other mesenchymal tumors<\/strong><\/p>\n<\/li>\n<li data-start=\"2995\" data-end=\"3060\">\n<p data-start=\"2997\" data-end=\"3060\">Research on <strong data-start=\"3009\" data-end=\"3058\">transmembrane proteins and oncogenic pathways<\/strong><\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"3062\" data-end=\"3065\" \/>\n<h3 data-start=\"3067\" data-end=\"3095\">\ud83c\udf10 Fardad Azma Rad Co.<\/h3>\n<p data-start=\"3097\" data-end=\"3460\"><strong data-start=\"3097\" data-end=\"3120\"><a href=\"https:\/\/fardadazma.com\/en\/about\/\">Fardad Azma Rad<\/a> Co.<\/strong>, the <strong data-start=\"3126\" data-end=\"3175\">exclusive representative of <a href=\"https:\/\/fardadazma.com\/en\/talent\/\">Talent Biomedical<\/a><\/strong> in Iran, provides high-quality <strong data-start=\"3207\" data-end=\"3242\">immunohistochemistry antibodies<\/strong>, including <strong data-start=\"3254\" data-end=\"3263\">DOG-1<\/strong>.<br data-start=\"3264\" data-end=\"3267\" \/>With a strong focus on <strong data-start=\"3290\" data-end=\"3367\">scientific precision, diagnostic reliability, and international standards<\/strong>, Fardad Azma Rad supports pathology and molecular diagnostic laboratories throughout Iran.<\/p>\n<p><a href=\"https:\/\/fardadazma.com\/wp-content\/uploads\/2025\/10\/DOG-1-Instruction-for-Use.pdf\"><strong>&#8220;Download Brochure&#8221;<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<table>\n<thead>\n<tr>\n<th><strong>Item<\/strong><\/th>\n<th><strong>Description<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Product Name<\/strong><\/td>\n<td>DOG-1 Antibody (Immunohistochemistry)<\/td>\n<\/tr>\n<tr>\n<td><strong>Application<\/strong><\/td>\n<td>Immunohistochemical detection of DOG-1 expression in GIST and related tumors<\/td>\n<\/tr>\n<tr>\n<td><strong>Antigen Localization<\/strong><\/td>\n<td>Membrane \/ Cytoplasm<\/td>\n<\/tr>\n<tr>\n<td><strong>Sample Type<\/strong><\/td>\n<td>FFPE tissue sections (3\u20135 \u00b5m)<\/td>\n<\/tr>\n<tr>\n<td><strong>Detection Method<\/strong><\/td>\n<td>IHC staining using DAB chromogen<\/td>\n<\/tr>\n<tr>\n<td><strong>Positive Control<\/strong><\/td>\n<td>GIST tissue<\/td>\n<\/tr>\n<tr>\n<td><strong>Available Volumes<\/strong><\/td>\n<td>0.2 ml, 1 ml, 3 ml, 6 ml, 11 ml<\/td>\n<\/tr>\n<tr>\n<td><strong>Storage Conditions<\/strong><\/td>\n<td>2\u20138 \u00b0C<\/td>\n<\/tr>\n<tr>\n<td><strong>Shelf Life<\/strong><\/td>\n<td>18 months from production date<\/td>\n<\/tr>\n<tr>\n<td><strong>Manufacturer<\/strong><\/td>\n<td>Talent Biomedical Technology Co., Ltd. \u2013 China<\/td>\n<\/tr>\n<tr>\n<td><strong>Exclusive Representative in Iran<\/strong><\/td>\n<td>Fardad Azma Rad Co.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"featured_media":1602,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[27],"product_tag":[904,897,898,900,901,899,902,903],"class_list":{"0":"post-1601","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-pathology","7":"product_tag-dog1-antibody","8":"product_tag-dog1-diagnostic-reagent","9":"product_tag-dog1-hrp-staining","10":"product_tag-dog1-immunohistochemistry","11":"product_tag-dog1-ivd-kit","12":"product_tag-ffpe-detection","13":"product_tag-gist-marker","14":"product_tag-ihc-antibody","16":"first","17":"instock","18":"shipping-taxable","19":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>DOG-1 Antibody (Immunohistochemistry) - Fardadazma<\/title>\n<meta name=\"description\" content=\"The DOG-1 Antibody 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