{"id":1455,"date":"2025-05-20T15:26:23","date_gmt":"2025-05-20T11:56:23","guid":{"rendered":"https:\/\/fardadazma.com\/en\/?post_type=product&#038;p=1455"},"modified":"2025-11-30T16:19:04","modified_gmt":"2025-11-30T12:49:04","slug":"realquality-rs-inv-16","status":"publish","type":"product","link":"https:\/\/fardadazma.com\/en\/product\/realquality-rs-inv-16\/","title":{"rendered":"REALQUALITY RS-INV 16"},"content":{"rendered":"<h2 data-start=\"212\" data-end=\"242\">REALQUALITY\u00ae RS-INV 16<\/h2>\n<h3 data-start=\"243\" data-end=\"313\">Detection and Quantification of inv(16)(p13;q22) Fusion Transcript<\/h3>\n<p data-start=\"315\" data-end=\"827\">The <a href=\"https:\/\/fardadazma.com\/product-category\/%d8%a2%d8%b2%d9%85%d8%a7%db%8c%d8%b4%da%af%d8%a7%d9%87%db%8c\/%da%98%d9%86%d8%aa%db%8c%da%a9\/?filter_brand=ab-analitica&amp;query_type_brand=or\"><strong data-start=\"319\" data-end=\"345\">REALQUALITY\u00ae RS-INV 16<\/strong> <\/a>kit, developed by <strong data-start=\"364\" data-end=\"388\"><a href=\"https:\/\/fardadazma.com\/product-category\/%d8%a2%d8%b2%d9%85%d8%a7%db%8c%d8%b4%da%af%d8%a7%d9%87%db%8c\/%da%98%d9%86%d8%aa%db%8c%da%a9\/?filter_brand=ab-analitica&amp;query_type_brand=or\">AB ANALITICA<\/a> (Italy)<\/strong>, is a <strong data-start=\"395\" data-end=\"435\">CE-IVD certified Real-Time PCR assay<\/strong> designed for the <strong data-start=\"453\" data-end=\"570\">identification and quantification of fusion transcripts resulting from the pericentric inversion of chromosome 16<\/strong>, known as <strong data-start=\"581\" data-end=\"601\">inv(16)(p13;q22)<\/strong>.<br data-start=\"602\" data-end=\"605\" \/>This chromosomal rearrangement involves the <strong data-start=\"649\" data-end=\"662\">CBF\u03b2 gene<\/strong> located in region <strong data-start=\"681\" data-end=\"690\">16q22<\/strong> and the <strong data-start=\"699\" data-end=\"713\">MYH11 gene<\/strong> located in region <strong data-start=\"732\" data-end=\"741\">16p13<\/strong>, which are commonly associated with <strong data-start=\"778\" data-end=\"824\">Acute Myeloid Leukemia (AML), subtype M4Eo<\/strong>.<\/p>\n<p data-start=\"829\" data-end=\"1170\">Detection of the <strong data-start=\"846\" data-end=\"878\">CBF\u03b2-MYH11 fusion transcript<\/strong> is a crucial marker for <strong data-start=\"903\" data-end=\"947\">diagnosis, classification, and prognosis<\/strong> in AML patients.<br data-start=\"964\" data-end=\"967\" \/>Using advanced <strong data-start=\"982\" data-end=\"1013\">Real-Time RT-PCR technology<\/strong>, the kit provides <strong data-start=\"1032\" data-end=\"1083\">high analytical sensitivity and reproducibility<\/strong> for both qualitative detection and quantitative monitoring of this molecular target.<\/p>\n<hr data-start=\"1172\" data-end=\"1175\" \/>\n<h3 data-start=\"1177\" data-end=\"1205\">\ud83c\udf10 Fardad Azma Rad Co.<\/h3>\n<p data-start=\"1206\" data-end=\"1650\"><strong data-start=\"1206\" data-end=\"1229\"><a href=\"https:\/\/fardadazma.com\/about\/\">Fardad Azma Rad<\/a> Co.<\/strong> is the <strong data-start=\"1237\" data-end=\"1289\">exclusive representative of AB ANALITICA (Italy)<\/strong> in Iran and the authorized distributor of the <strong data-start=\"1336\" data-end=\"1367\">REALQUALITY\u00ae ONCOHEMATOLOGY<\/strong> product line, including the <strong data-start=\"1396\" data-end=\"1413\">RS-INV 16 kit<\/strong>.<br data-start=\"1414\" data-end=\"1417\" \/>With a strong focus on <strong data-start=\"1440\" data-end=\"1525\">diagnostic accuracy, product quality, and compliance with international standards<\/strong>,<br data-start=\"1526\" data-end=\"1529\" \/>Fardad Azma Rad provides advanced molecular diagnostic solutions to <strong data-start=\"1597\" data-end=\"1635\">clinical and research laboratories<\/strong> across Iran.<\/p>\n<hr data-start=\"1652\" data-end=\"1655\" \/>\n<h3 data-start=\"1657\" data-end=\"1691\">\ud83d\udd2c Key Features and Benefits<\/h3>\n<ul data-start=\"1692\" data-end=\"2457\">\n<li data-start=\"1692\" data-end=\"1779\">\n<p data-start=\"1694\" data-end=\"1779\">Detects and quantifies the <strong data-start=\"1721\" data-end=\"1753\">CBF\u03b2-MYH11 fusion transcript<\/strong> associated with inv(16)<\/p>\n<\/li>\n<li data-start=\"1780\" data-end=\"1872\">\n<p data-start=\"1782\" data-end=\"1872\"><strong data-start=\"1782\" data-end=\"1802\">CE-IVD certified<\/strong> and fully compliant with <strong data-start=\"1828\" data-end=\"1859\">Europe Against Cancer (EAC)<\/strong> guidelines<\/p>\n<\/li>\n<li data-start=\"1873\" data-end=\"1930\">\n<p data-start=\"1875\" data-end=\"1930\"><strong data-start=\"1875\" data-end=\"1928\">Validated on RNA extracted from leukocyte pellets<\/strong><\/p>\n<\/li>\n<li data-start=\"1931\" data-end=\"2020\">\n<p data-start=\"1933\" data-end=\"2020\">Requires <strong data-start=\"1942\" data-end=\"1958\">5 \u00b5L of cDNA<\/strong> equivalent to <strong data-start=\"1973\" data-end=\"2005\">1 \u00b5g of retrotranscribed RNA<\/strong> per reaction<\/p>\n<\/li>\n<li data-start=\"2021\" data-end=\"2110\">\n<p data-start=\"2023\" data-end=\"2110\">Includes <strong data-start=\"2032\" data-end=\"2076\">dUTP\/UNG contamination prevention system<\/strong> and <strong data-start=\"2081\" data-end=\"2108\">fluorescence normalizer<\/strong><\/p>\n<\/li>\n<li data-start=\"2111\" data-end=\"2174\">\n<p data-start=\"2113\" data-end=\"2174\">Contains <strong data-start=\"2122\" data-end=\"2143\">positive controls<\/strong> for both INV16 and ABL genes<\/p>\n<\/li>\n<li data-start=\"2175\" data-end=\"2275\">\n<p data-start=\"2177\" data-end=\"2275\">Allows <strong data-start=\"2184\" data-end=\"2223\">quantification of INV16 transcripts<\/strong> when used with <strong data-start=\"2239\" data-end=\"2273\">REALQUALITY RQ-INV 16 STANDARD<\/strong><\/p>\n<\/li>\n<li data-start=\"2276\" data-end=\"2361\">\n<p data-start=\"2278\" data-end=\"2361\">Shares identical thermal cycling profile with <strong data-start=\"2324\" data-end=\"2339\">RS-AML1-ETO<\/strong> and <strong data-start=\"2344\" data-end=\"2354\">RS-WT1<\/strong> kits<\/p>\n<\/li>\n<li data-start=\"2362\" data-end=\"2457\">\n<p data-start=\"2364\" data-end=\"2457\"><strong data-start=\"2364\" data-end=\"2414\">Validated on major Real-Time PCR thermocyclers<\/strong> commonly used in diagnostic laboratories<\/p>\n<\/li>\n<\/ul>\n<p class=\"\" data-start=\"94\" data-end=\"422\"><a href=\"\/wp-content\/uploads\/2025\/02\/20240322-ONCHOEMATOLOGY_brochure-11_11zon.pdf\"><strong>Download Catalog<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<table>\n<thead>\n<tr>\n<th><strong>Parameter<\/strong><\/th>\n<th><strong>Description<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Product Name<\/strong><\/td>\n<td>REALQUALITY\u00ae RS-INV 16<\/td>\n<\/tr>\n<tr>\n<td><strong>Application<\/strong><\/td>\n<td>Detection and quantification of the CBF\u03b2-MYH11 fusion transcript in AML patients<\/td>\n<\/tr>\n<tr>\n<td><strong>Assay Type<\/strong><\/td>\n<td>One-Step Real-Time RT-PCR<\/td>\n<\/tr>\n<tr>\n<td><strong>Sample Type<\/strong><\/td>\n<td>RNA extracted from leukocyte pellet<\/td>\n<\/tr>\n<tr>\n<td><strong>Reaction Volume<\/strong><\/td>\n<td>5 \u00b5L of cDNA equivalent to 1 \u00b5g retrotranscribed RNA<\/td>\n<\/tr>\n<tr>\n<td><strong>Positive Controls<\/strong><\/td>\n<td>INV16 (fusion DNA) and ABL (reference gene DNA)<\/td>\n<\/tr>\n<tr>\n<td><strong>Contamination Control<\/strong><\/td>\n<td>dUTP\/UNG system and fluorescence normalization<\/td>\n<\/tr>\n<tr>\n<td><strong>Compatibility<\/strong><\/td>\n<td>Validated on major Real-Time PCR instruments<\/td>\n<\/tr>\n<tr>\n<td><strong>Quantification Option<\/strong><\/td>\n<td>Available using the REALQUALITY RQ-INV 16 STANDARD kit<\/td>\n<\/tr>\n<tr>\n<td><strong>Storage Conditions<\/strong><\/td>\n<td>2\u20138 \u00b0C<\/td>\n<\/tr>\n<tr>\n<td><strong>Shelf Life<\/strong><\/td>\n<td>18 months from production date<\/td>\n<\/tr>\n<tr>\n<td><strong>Certifications<\/strong><\/td>\n<td>CE-IVD, EAC-Compliant<\/td>\n<\/tr>\n<tr>\n<td><strong>Manufacturer<\/strong><\/td>\n<td>AB ANALITICA srl \u2013 Italy<\/td>\n<\/tr>\n<tr>\n<td><strong>Exclusive Representative in Iran<\/strong><\/td>\n<td>Fardad Azma Rad Co.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"featured_media":1456,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[28],"product_tag":[372,401,398,403,402,399,400,245,404],"class_list":{"0":"post-1455","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-genetics","7":"product_tag-acute-myeloid-leukemia-aml","8":"product_tag-cbf-and-myh11-genes","9":"product_tag-fluorescence-normalizer-rox","10":"product_tag-inv16-fusion-transcripts","11":"product_tag-inv16p13q22-chromosomal-rearrangement","12":"product_tag-minimal-residual-disease-mrd-monitoring","13":"product_tag-molecular-diagnosis-of-aml","14":"product_tag-real-time-pcr","15":"product_tag-realquality-rs-inv-16-kit","17":"first","18":"instock","19":"shipping-taxable","20":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - 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