SATB-2 Antibody (Immunohistochemistry)

The SATB-2 Antibody is a highly specific immunohistochemical marker widely used for identifying
colorectal and appendiceal adenocarcinomas and distinguishing them from metastatic tumors of other origins.
SATB-2 (Special AT-rich Sequence-Binding Protein 2) is a
nuclear matrix-associated transcription factor involved in regulating gene expression in
neuronal and intestinal epithelial cells.

In diagnostic pathology, SATB-2 is especially valuable for detecting
colorectal carcinoma, appendiceal neoplasms, and certain
bone-related tumors (e.g., osteosarcoma).
Positive IHC staining appears as
distinct brown nuclear coloration.
When combined with CK20 and CDX2, SATB-2 significantly improves diagnostic accuracy.

🔬 Features and Benefits

• Highly specific marker for colorectal adenocarcinoma
• Distinct nuclear brown staining
• Differentiates colorectal tumors from metastatic carcinomas
• Can be used alongside CK20 and CDX2 for increased precision
• Excellent stability: 18-month shelf life at 2–8 °C

💡 Diagnostic Applications

• Detection of colorectal and appendiceal adenocarcinomas
• Differentiation from ovarian, pancreatic, and pulmonary carcinomas
• Identification of SATB-2 expression in bone-related tumors
• Research on gene transcription and cell differentiation

🌐 Fardad Azma Rad Co.

Fardad Azma Rad Co., the
exclusive representative of Talent Biomedical in Iran, supplies high-quality
immunohistochemistry antibodies, including SATB-2.
The company is committed to
scientific excellence, diagnostic reliability, and international standards, supporting pathology and molecular diagnostic laboratories throughout Iran.

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