p40 Antibody (Immunohistochemistry)

The p40 Antibody is a highly specific immunohistochemical marker used for the differential diagnosis of squamous cell carcinoma (SCC), particularly in the lung, from adenocarcinoma.
p40 is an isoform of the p63 transcription factor, involved in cell proliferation, differentiation, and maintenance.
Compared to p63, p40 provides greater specificity because it is rarely expressed in lung adenocarcinomas, making it the preferred marker for differentiating lung SCC from adenocarcinoma.

Positive IHC staining for p40 shows brown nuclear staining in squamous cells, aiding in accurate histopathological identification.

🔬 Features and Benefits

• Highly specific marker for squamous cell carcinoma

• Superior specificity compared to p63

• Distinct brown nuclear staining pattern

• Useful in diagnosing epithelial tumors of the lung, prostate, breast, and urinary tract

• Excellent stability: 18-month shelf life at 2–8 °C

💡 Diagnostic Applications

• Differential diagnosis of Lung SCC vs. Lung Adenocarcinoma

• Identification of Urothelial and Myoepithelial Tumors

• Detection of Basal cells in prostate and epithelial layers

• Evaluation of Squamous differentiation in various tissues

🌐 Fardad Azma Rad Co.

Fardad Azma Rad Co., the exclusive representative of Talent Biomedical in Iran, supplies high-quality immunohistochemistry antibodies, including p40.
With a commitment to scientific precision, diagnostic reliability, and international quality standards, Fardad Azma Rad supports pathology and molecular diagnostic centers across Iran.

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