MSH2 Antibody (Immunohistochemistry)

MSH2 Antibody (Immunohistochemistry)

The MSH2 Antibody is an essential marker in Mismatch Repair (MMR) pathway diagnostics, particularly for detecting colorectal cancer and genetic disorders.
MSH2 is part of the DNA mismatch repair system, responsible for correcting DNA replication errors. When MSH2 expression is absent, it may lead to the development of conditions like Hereditary Nonpolyposis Colorectal Cancer (HNPCC).

IHC staining for MSH2 typically appears as brown nuclear staining in positive cells. The antibody is often paired with MSH6, MLH1, and PMS2 to improve diagnostic accuracy, particularly for microsatellite instability (MSI) testing and evaluating cancer therapy responses.

🔬 Features and Benefits MSH2 Antibody

• Key marker in colorectal cancer diagnosis and genetic abnormalities

• Clear brown nuclear staining pattern

• Ideal for detecting MMR-related genetic disorders

• Compatible with standard IHC protocols

• Excellent stability: 18-month shelf life at 2–8 °C

💡 Diagnostic Applications

• Detection of colorectal cancer and MMR gene mutations

• Microsatellite Instability (MSI) testing in tumors

• Hereditary Nonpolyposis Colorectal Cancer (HNPCC)

• Identification of MMR pathway mutations

🌐 Fardad Azma Rad Co.

Fardad Azma Rad Co., the exclusive representative of Talent Biomedical in Iran, supplies high-quality immunohistochemistry antibodies, including MSH2.
With a focus on scientific accuracy, diagnostic reliability, and international standards, Fardad Azma Rad supports pathology laboratories and molecular diagnostic centers throughout Iran.

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