Glypican-3 (GPC3) Antibody – Immunohistochemistry
Exclusive Distributor of Talent Biomedical in Iran
The Glypican-3 (GPC3) Antibody is designed for the detection of GPC3 in tissue sections using immunohistochemistry.
Glypican-3 is a membrane-associated protein that helps regulate tissue and organ growth.
What Is Glypican-3?
GPC3 is part of the glypican family of heparan sulfate proteoglycans. It interacts with growth factors such as IGF-II and FGF-2.
High expression of GPC3 is commonly seen in liver-related cancers and several embryonal tumors.
Why This Antibody Is Important
Glypican-3 is widely used as a tumor marker. It is especially valuable in diagnosing hepatocellular carcinoma (HCC), hepatoblastoma
, melanoma, and testicular germ cell tumors. It can also help identify tumors such as Wilms’ tumor.
How the Antibody Works
This antibody binds specifically to GPC3 in tissue samples. Using a DAB chromogenic solution
, the target cells become visible as a brown stain, allowing accurate interpretation.
Key Features
- Specific detection of Glypican-3
- Useful for diagnosing HCC, hepatoblastoma, melanoma, and germ cell tumors
- Clear and fast visualization with DAB chromogen
- Positive Localization: Cytoplasm
Clinical Applications
- Hepatocellular carcinoma
- Hepatoblastoma
- Melanoma
- Testicular germ cell tumors
- Wilms’ tumor and embryonal tumors Distributor Information
Fardad Azma Rad is the exclusive distributor of Talent Biomedical in Iran,
providing high-quality antibodies and full technical support for immunohistochemistry applications.
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