Cyclin D1 Antibody (Immunohistochemistry)

Cyclin D1 Antibody (Immunohistochemistry)

The Cyclin D1 Antibody is a key immunohistochemical marker used for detecting Mantle Cell Lymphoma (MCL) and other tumors such as breast, colon, prostate, melanoma, and parathyroid adenomas.
Cyclin D1 is a cell cycle regulatory protein that controls the transition from the G1 to S phase by activating the Cyclin D1–CDK4/6 complex, promoting cell proliferation.

Overexpression or gene amplification of Cyclin D1 plays a critical role in the development of various human tumors, making it a valuable molecular marker in both clinical diagnosis and research.
Positive staining is typically nuclear, appearing as brown coloration in tumor cells, indicating abnormal cell proliferation.

🔬 Features and Benefits Cyclin D1 Antibody

• Specific marker for Mantle Cell Lymphoma and carcinomas

• Distinct nuclear brown staining

• Useful for studying cell cycle regulation and oncogenesis

• Compatible with standard IHC protocols

• Excellent stability: 18-month shelf life at 2–8 °C

💡 Diagnostic Applications

• Detection of Mantle Cell Lymphoma (MCL)

• Evaluation of breast, prostate, and colon carcinomas

• Research on cell cycle and tumor proliferation mechanisms

• Differentiation between neoplastic and reactive lymphoid proliferations

🌐 Fardad Azma Rad Co.

Fardad Azma Rad Co., the exclusive representative of Talent Biomedical in Iran, provides high-quality immunohistochemistry antibodies, including Cyclin D1.
With dedication to scientific accuracy, diagnostic precision, and international standards, the company supports pathology laboratories and molecular diagnostic centers across Iran.

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