β-Catenin Antibody (Immunohistochemistry)

β-Catenin Antibody (Immunohistochemistry)

The β-Catenin Antibody is a key marker used to study the Wnt signaling pathway and identify tumors associated with its dysregulation.
β-Catenin is a 92 kDa cytoplasmic and nuclear glycoprotein that plays dual roles in cell adhesion (via E-Cadherin) and transcriptional regulation.

In normal cells, β-Catenin is localized to the cell membrane, but abnormal activation or mutation of the Wnt pathway results in nuclear translocation, which activates genes related to tumor proliferation.
Thus, β-Catenin IHC staining is crucial for diagnosing Desmoid Tumor, Hepatocellular Carcinoma, Colorectal Carcinoma, and Medulloblastoma.

🔬 Features and Benefits β-Catenin Antibody

• Specific marker for Wnt/β-Catenin signaling alterations

• Distinct nuclear, cytoplasmic, or membranous staining pattern

• Widely applicable to colorectal, hepatic, and soft tissue tumors

• Compatible with standard IHC protocols

• Excellent stability: 18-month shelf life at 2–8 °C

💡 Diagnostic Applications

• Detection of Desmoid Fibromatosis (Aggressive Fibromatosis)

• Diagnosis of Colorectal and Hepatocellular Carcinomas

• Identification of Medulloblastoma and Ovarian Endometrioid Tumors

• Research on Wnt/β-Catenin signaling pathway

🌐 Fardad Azma Rad Co.

Fardad Azma Rad Co., the exclusive representative of Talent Biomedical in Iran, provides high-quality immunohistochemistry antibodies, including β-Catenin.
With commitment to diagnostic precision, scientific integrity, and international quality standards, the company supports pathology laboratories and research institutions across Iran.

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