SMA (Smooth Muscle Actin) Antibody (Immunohistochemistry)
The SMA (Smooth Muscle Actin) Antibody is a key marker used for identifying smooth muscle cells and myofibroblasts, playing an essential role in differentiating tumors of smooth muscle and myoepithelial origin.
SMA belongs to the actin family of cytoskeletal proteins, forming microfilaments that maintain cell structure and contractility.
In pathology, SMA shows positive cytoplasmic staining in smooth muscle tumors such as leiomyoma and leiomyosarcoma, as well as in myofibroblasts and myoepithelial cells.
This antibody is valuable for distinguishing muscle-derived tumors from other soft tissue neoplasms.
🔬 Features and Benefits SMA (Smooth Muscle Actin) Antibody
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Specific marker for smooth muscle and myofibroblastic differentiation
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Distinct brown cytoplasmic staining
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Useful for identifying leiomyosarcoma and vascular tumors
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Compatible with standard IHC protocols
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Excellent stability: 18-month shelf life at 2–8 °C
💡 Diagnostic Applications
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Detection of Leiomyoma and Leiomyosarcoma
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Identification of Myofibroblast and Myoepithelial Cells
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Evaluation of Vascular and Soft Tissue Tumors
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Differentiation of Smooth Muscle Sarcomas from other neoplasms
🌐 Fardad Azma Rad Co.
Fardad Azma Rad Co., the exclusive representative of Talent Biomedical in Iran, provides high-quality immunohistochemistry antibodies, including SMA.
The company is committed to diagnostic precision, scientific excellence, and international quality, serving pathology laboratories and molecular diagnostic centers across Iran.

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