p53 Antibody (Immunohistochemistry)

p53 Antibody (Immunohistochemistry)

The p53 Antibody is one of the most widely used tumor markers in molecular pathology and plays a crucial role in the diagnosis and prognosis of various malignancies.
p53, also known as Tumor Protein 53 (TP53), is a tumor suppressor and transcription factor that regulates DNA repair, cell cycle arrest, and apoptosis in response to DNA damage.

Mutations in the p53 gene lead to the loss of its tumor-suppressive functions and are associated with many cancers, including breast, lung, colon, bladder, ovary, and melanoma.
In immunohistochemistry, p53 typically shows brown nuclear staining in positive cells.

🔬 Features and Benefits p53 Antibody

• Standard marker for detecting p53 gene mutations

• Applicable to both epithelial and non-epithelial malignancies

• Distinct brown nuclear staining pattern

• Compatible with FFPE tissues and DAB chromogen systems

• Excellent stability: 18-month shelf life at 2–8 °C

💡 Diagnostic Applications

• Detection of p53 overexpression or mutation in tumors

• Diagnosis of breast, ovarian, bladder, lung, colon, and skin cancers

• Evaluation of tumor prognosis and treatment response

• Research on tumor suppression and cell cycle regulation

🌐 Fardad Azma Rad Co.

Fardad Azma Rad Co., the exclusive representative of Talent Biomedical in Iran, supplies high-quality immunohistochemistry antibodies, including p53.
With a commitment to scientific precision, diagnostic reliability, and international standards, Fardad Azma Rad supports pathology and molecular diagnostic laboratories across Iran.

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